Russian Journal of Bioorganic Chemistry

, Volume 29, Issue 2, pp 101–111 | Cite as

Brachyurins, Serine Collagenolytic Enzymes from Crabs

  • G. N. Rudenskaya


The properties of brachyurins, proteolytic enzymes belonging to a new subfamily of chymotrypsin-like proteases, are considered. These enzymes, found in various species of crustacean, exhibit mixed substrate specificity and a marked collagenolytic activity. The enzymatic and physicochemical properties of brachyurins I and their primary and spatial structures are discussed in detail. A separate chapter is devoted to the preparations of collagenases from the hepatopancreas of king crab: their action on the damaged skin and use in medicine.

brachyurins collagenolytic enzymes from crabs medicinal use properties 


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© MAIK “Nauka/Interperiodica” 2003

Authors and Affiliations

  • G. N. Rudenskaya
    • 1
  1. 1.Chemical FacultyMoscow State UniversityMoscowRussia

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