Diabetes Insipidus

  • Joseph G. Verbalis
arginine vasopressin desmopressin diabetes insipidus hypernatremia hyponatremia hyperosmolality hypoosmolality osmoreceptor 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Verbalis JG. The syndrome of inappropriate antidiuretic hormone secretion and other hypoosmolar disorders. In: Schrier RW, ed. Diseases of the Kidney and Urinary Tract, Seventh ed. Philadelphia: Lippincott Williams &; Wilkins, 2001:2511–2548.Google Scholar
  2. 2.
    Katz MA. Hyperglycemia-induced hyponatremia—Calculation of expected serum sodium depression. New England Journal of Medicine 1973;289:843–844.Google Scholar
  3. 3.
    Hillier TA, Abbott RD, Barrett EJ. Hyponatremia: Evaluating the correction factor for hyperglycemia. American Journal of Medicine 1999;106(4):399–403.Google Scholar
  4. 4.
    Phillips PA, Rolls BJ, Ledingham JG, Forsling ML, Morton JJ, Crowe MJ, Wollner L. Reduced thirst after water deprivation in healthy elderly men. N Engl J Med 1984;311(12):753–759.Google Scholar
  5. 5.
    Robertson GL. Posterior pituitary. In: Felig P, Baxter J, Frohman L, eds. Endocrinology and Metabolism. New York: McGraw-Hill, 1995:385–432.Google Scholar
  6. 6.
    Fujiwara TM, Morgan K, Bichet DG. Molecular biology of diabetes insipidus. Annual Review of Medicine 1995;46:331–343.Google Scholar
  7. 7.
    Robinson AG. Disorders of antidiuretic hormone secretion. Clin Endocrinol Metab 1985;14:55–88.Google Scholar
  8. 8.
    Knepper MA, Verbalis JG, Nielsen S. Role of aquaporins in water balance disorders. Curr Opin Nephrol Hypertens 1997;6(4):367–371.Google Scholar
  9. 9.
    Zerbe RL, Robertson GL. Acomparison of plasma vasopressin measurements with a standard indirect test in the differential diagnosis of polyuria. New England Journal of Medicine 1981;305:1539–1546.Google Scholar
  10. 10.
    Robertson GL. Diabetes insipidus. Endocrinol Metab Clin North Am 1995;24(3):549–572.Google Scholar
  11. 11.
    Robertson GL. Dipsogenic diabetes insipidus: A newly recognized syndrome caused by a selective defect in the osmoregulation of thirst. Transactions of the Association of American Physicians 1987;100:241–249.Google Scholar
  12. 12.
    Thrasher TN, Keil LC, Ramsay DJ. Lesions of the organum vasculosum of the lamina terminalis (OVLT) attenuate osmoticallyinduced drinking and vasopressin secretion in the dog. Endocrinology 1982;110(5):1837–1839.Google Scholar
  13. 13.
    Johnson AK, Buggy J. Periventricular preoptic-hypothalamus is vital for thirst and normal water economy. Am J Physiol 1978;234(3):R122–R129.Google Scholar
  14. 14.
    Baylis PH, Thompson CJ. Diabetes insipidus and hyperosmolar syndromes. In: Becker KL, ed. Principles and Practice of Endocrinology and Metabolism, 3rd ed. Philadelphia: Lippincott Williams &; Wilkins, 2001:285–293.Google Scholar
  15. 15.
    Gullans SR, Verbalis JG. Control of brain volume during hyperosmolar and hypoosmolar conditions. Annual Review of Medicine 1993;44:289–301.Google Scholar
  16. 16.
    Verbalis JG, Robinson AG, Moses AM. Postoperative and post-traumatic diabetes insipidus. In: Czernichow P, Robinson AG, eds. Diabetes Insipidus in Man. Basel: Karger, 1984:247–265.Google Scholar
  17. 17.
    Cusick JF, Hagen TC, Findling JW. Inappropriate secretion of antidiuretic hormone after transsphenoidal surgery for pituitary tumors. New England Journal of Medicine 1984;311:36–38.Google Scholar
  18. 18.
    Olson BR, Rubino D, Gumowski J, Oldfield EH. Isolated hyponatremia after transsphenoidal pituitary surgery. Jounal of Clinical Endocrinology and Metabolism 1995;80(1):85–91.Google Scholar
  19. 19.
    Ultmann MC, Hoffman GE, Nelson PB, Robinson AG. Transient hyponatremia after damage to the neurohypophyseal tracts. Neuroendocrinology 1992;56(6):803–811.Google Scholar
  20. 20.
    Robinson AG, Verbalis JG. Diabetes insipidus. Curr Ther Endocrinol Metab 1997;6:1–7.Google Scholar

Copyright information

© Kluwer Academic Publishers 2003

Authors and Affiliations

  • Joseph G. Verbalis
    • 1
  1. 1.Georgetown University School of MedicineWashington D.C.USA

Personalised recommendations