Journal of Assisted Reproduction and Genetics

, Volume 20, Issue 4, pp 157–159 | Cite as

Short Communication: Does Preejaculatory Penile Secretion Originating from Cowper's Gland Contain Sperm?

  • Zvi Zukerman
  • David B. Weiss
  • Raoul Orvieto


Purpose: To determine if spermatozoa are present in the preejaculatory penile secretion, originating from Cowper's gland.

Methods:Design: Prospective clinical and laboratory study. Setting: Andrology and Sex Counseling Unit, Department of Obstetrics and Gynecology, Academic Teaching Hospital. Patients: Five patients referred for premature ejaculation, three for excessive fluid secreted during foreplay and four normal healthy volunteers. Intervention: Glass slide smears of preejaculatory Cowper's gland secretion obtained during foreplay from at least two different occasions, and semen samples after masturbation. Main Outcome Measures: Microscopic examination of air-dried smears, and routine semen analyses.

Results: None of the preejaculatory samples contained sperm. All the patients had sperm in routine sperm analyses.

Conclusions: Preejaculatory fluid secreted at the tip of the urethra from Cowper's gland during sexual stimulation did not contain sperm and therefore cannot be responsible for pregnancies during coitus interruptus.

Cowper's gland ejaculation sperm 


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Copyright information

© Plenum Publishing Corporation 2003

Authors and Affiliations

  • Zvi Zukerman
    • 1
    • 2
  • David B. Weiss
    • 3
  • Raoul Orvieto
    • 1
    • 2
  1. 1.Andrology Unit, Department of Obstetrics and GynecologyRabin Medical CenterPetah TikvaIsrael
  2. 2.Sackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael
  3. 3.Male Infertility ClinicKupat Holim Me'uhedetJerusalemIsrael

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