Journal of Medical Systems

, Volume 22, Issue 2, pp 89–93

Influence of Smoking on Serum Carcinoembryonic Antigen Levels in Subjects Who Underwent Multiphasic Health Testing and Services

  • I. Fukuda
  • M. Yamakado
  • H. Kiyose

DOI: 10.1023/A:1022643102208

Cite this article as:
Fukuda, I., Yamakado, M. & Kiyose, H. Journal of Medical Systems (1998) 22: 89. doi:10.1023/A:1022643102208


We quantified the effect of smoking on serum carcinoembryonic antigen (CEA) levels in 1341 subjects who underwent the multiphasic health testing and services in our center. Four hundred and sixty seven of them were smokers and the rest were nonsmokers. In male subjects, serum CEA levels were significantly higher in smokers (3.11 ±1.8 ng/ml) than in nonsmokers (2.14 ± 1.8 ng/ml) (mean ± SD;p < 0.01). For females, however, the levels had no significant differences between smokers (2.11 ± 0.91 ng/ml) and nonsmokers (1.87 ± 1.3 ng/ml). The CEA-positive subjects were 44, of whom 32 were male custom heavy smokers, and only 2 of them had gastrointestinal cancer. We concluded that the serum CEA level was influenced by smoking especially in males and its clinical significance for detection of carcinoma was doubtful.

carcinoembryonic antigen smoking gastrointestinal cancer multiphasic health testing and services 

Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • I. Fukuda
  • M. Yamakado
  • H. Kiyose

There are no affiliations available

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