Cognitive Therapy and Research

, Volume 21, Issue 4, pp 409–420 | Cite as

Life Event, Mood, and Cognitive Predictors of Perceived Stress Before and After Treatment for Major Depression

  • Michael W. Otto
  • Maurizio Fava
  • Susan J. Penava
  • Elizabeth Bless
  • Robert T. Muller
  • Jerrold F. Rosenbaum


Using regression models, we examined the influence of negative life events, depression severity, dysfunctional attitudes, and problem-solving ability on the perceived stress of depressed outpatients before and after antidepressant treatment. The report of negative life events predicted the level of perceived stress in untreated patients, but was not a significant predictor after treatment. Depression severity, dysfunctional attitudes, and problem-solving ability were associated with each other, improved with treatment, and associated with perceived stress before and after treatment. These findings are consistent with the hypothesis that less adaptive coping strategies are applied under conditions of mood disturbance, and that these strategies are in turn linked with increased stress.

depression dysfunctional attitudes problem solving perceived stress negative life events 


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Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • Michael W. Otto
    • 1
  • Maurizio Fava
    • 1
  • Susan J. Penava
    • 1
  • Elizabeth Bless
    • 1
  • Robert T. Muller
    • 1
  • Jerrold F. Rosenbaum
    • 1
  1. 1.Massachusetts General Hospital and Harvard Medical SchoolBoston

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