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Molecular Biology

, Volume 36, Issue 6, pp 802–812 | Cite as

Diversity of Mitochondrial DNA Haplogroups in Ethnic Populations of the Volga–Ural Region

  • M. A. Bermisheva
  • K. Tambets
  • R. Villems
  • E. K. Khusnutdinova
Article

Abstract

The mtDNA polymorphism was analyzed in eight ethnic groups (N = 979) of the Volga–Ural region. Most mtDNA variants belonged to haplogroups H, U, T, J, W, I, R, and N1 characteristic of West Eurasian populations. The most frequent were haplogroups H (12–42%) and U (18–44%). East Eurasian mtDNA types (A, B, Y, F, M, N9) were also observed. Genetic diversity was higher in Turkic than in Finno-Ugric populations. The frequency of mtDNA types characteristic of Siberian and Central Asian populations substantially increased in the ethnic groups living closer to the Urals, a boundary between Europe and Asia. Geographic distances, rather than linguistic barriers, were assumed to play the major role in distribution of mtDNA types in the Volga–Ural region. Thus, as concerns the maternal lineage, the Finno-Ugric populations of the region proved to be more similar to their Turkic neighbors rather than to linguistically related Balto-Finnish ethnic groups.

mitochondrial DNA haplotyping ethnogenomics ethnic groups of the Volga–Ural region 

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REFERENCES

  1. 1.
    Cann, R., Stoneking, M., and Wilson, A., Nature, 1987, vol. 325, pp. 31–36.Google Scholar
  2. 2.
    Wallace, D.C., Brown, M.D., and Lott, M.T., Gene, 1999, vol. 238, pp. 211–230.Google Scholar
  3. 3.
    Denaro, M., Blanc, H., Johnson, M.J., et al., Proc. Natl. Acad. Sci. USA, 1981, vol. 78, pp. 5768–5772.Google Scholar
  4. 4.
    Macaulay, V., Richards, M., Hickey, E., et al., Am. J. Hum. Genet., 1999, vol. 58, pp. 1309–1322.Google Scholar
  5. 5.
    Richards, M., Macaulay, V., and Bandelt, H.J., Ann. Hum. Genet., 1998, vol. 62, pp. 241–260.Google Scholar
  6. 6.
    Torroni, A., Huoponen, K., Francalacci, P., et al., Genetics, 1996, vol. 144, pp. 1835–1850.Google Scholar
  7. 7.
    Richards, M., Corte-Real, H., et al., Am. J. Hum. Genet., 1996, vol. 59, pp. 185–203.Google Scholar
  8. 8.
    Torroni, A., Lott, M., Cabell, M., et al., Am. J. Hum. Genet., 1994, vol. 55, pp. 760–776.Google Scholar
  9. 9.
    Torroni, A., Schurr, T., Yang, C., et al., Genetics, 1992, vol. 130, pp. 153–162.Google Scholar
  10. 10.
    Torroni, A., Schurr, T., Cabell, M., et al., Am. J. Hum. Genet., 1993, vol. 53, pp. 563–590.Google Scholar
  11. 11.
    Cavalli-Sforza, L., Menozzi, P., and Piazza, A., The History and Geography of Human Genes, Princeton: Princeton Univ. Press, 1994.Google Scholar
  12. 12.
    Kuzeev, R.G., Narody srednego Povolzh'ya i Yuzhnogo Urala (Ethnic Groups of the Central Volga Region and Southern Urals), Moscow: Nauka, 1992.Google Scholar
  13. 13.
    Anderson, S., Bankier, A.T., Barrell, B.G., et al., Nature, 1981, vol. 290, pp. 457–465.Google Scholar
  14. 14.
    Nei, M., Molecular Evolutionary Genetics, New York: Columbia Univ. Press, 1988.Google Scholar
  15. 15.
    Richards, M., Macaulay, V., Hickey, E., et al., Am. J. Hum. Genet., 2000, vol. 67, pp. 1251–1276.Google Scholar
  16. 16.
    Torroni, A., Bandelt, H.J., Macaulay, V., et al., Am. J. Hum. Genet., 2001, vol. 69, pp. 844–852.Google Scholar
  17. 17.
    Lahermo, P., Sajantila, A., Sistonen, P., et al., Am. J. Hum. Genet., 1996, vol. 58, pp. 1309–1322.Google Scholar
  18. 18.
    Lahermo, P., Sajantila, A., Sistonen, P., et al., Am. J. Hum. Genet., 1999, vol. 64, pp. 232–249.Google Scholar
  19. 19.
    Sajantila, A., Lahermo, P., Anttinen, T., et al., Genome Res., 1995, vol. 5, pp. 42–52.Google Scholar
  20. 20.
    Meinilä, M., Finillä, S., and Majamaa, K., Hum. Hered., 2001, vol. 52, pp. 160–170.Google Scholar
  21. 21.
    Kivisild, T., Kaldma, K., Metspalu, M., et al., in Genomic Diversity, Kluwer Academic, 1999, pp. 135–152.Google Scholar
  22. 22.
    Comas, D., Calafell, F., Mateu, E., et al., Am. J. Hum. Genet., 1998, vol. 63, pp. 1824–1838.Google Scholar
  23. 23.
    Metspalu, E., Kivisild, T., Kaldma, K., et al., in Genomic Diversity, Kluwer Academic, 1999, pp. 121–134.Google Scholar
  24. 24.
    Finillä, S. and Majamaa, K., J. Hum. Genet., 2001, vol. 46, pp. 64–69.Google Scholar
  25. 25.
    Schurr, T., Sukernik, R., Starikovskaya, Y., et al., Am. J. Phys. Anthropol., 1999, vol. 108, pp. 1–39.Google Scholar
  26. 26.
    Starikovskaya, Y., Sukernik, R., Schurr, T., et al., Am. J. Hum. Genet., 1998, vol. 63, pp. 1473–1491.Google Scholar
  27. 27.
    Villems, R., Adojaan, M., Kivisild, T., et al., The Roots of Peoples and Languages of Northern Eurasia, vol. 1, Wiik, K. and Julku, K., Eds., Turku: Societas Historiae Fenno-Ugricae, 1998.Google Scholar
  28. 28.
    Kolman, C. and Sambuughin, N., Genetics, 1996, vol. 142, pp. 1321–1334.Google Scholar
  29. 29.
    Torroni, A., Sukernik, R.I., Schurr, T.G., et al., Am. J. Hum. Genet., 1993, vol. 53, pp. 591–608.Google Scholar
  30. 30.
    Bermisheva, M.A., Viktorova, T.V., and Khusnutdinova, E.K., Genetika, 2001, vol. 37, pp. 1002–1007.Google Scholar
  31. 31.
    Derenko, M., Malyarchuk, B., Dambueva, I., et al., Hum. Biol., 2000, vol. 72, pp. 945–973.Google Scholar

Copyright information

© MAIK “Nauka/Interperiodica” 2002

Authors and Affiliations

  • M. A. Bermisheva
    • 1
  • K. Tambets
    • 2
  • R. Villems
    • 2
  • E. K. Khusnutdinova
    • 1
  1. 1.Institute of Biochemistry and Genetics, Ufa Research CenterRussian Academy of SciencesUfaRussia
  2. 2.Estonian Biological CenterTartu UniversityTartuEstonia

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