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Behavior Genetics

, Volume 28, Issue 3, pp 165–171 | Cite as

The Heritability of Testosterone: A Study of Dutch Adolescent Twins and Their Parents

  • Julie Aitken Harris
  • Philip A. Vernon
  • Dorret I. Boomsma
Article

Abstract

The heritability of total plasma testosterone levels, determined from blood samples, was examined in 160 adolescent twin pairs and their parents. Subjects were tested as part of a larger study of cardiovascular risk factors, conducted in Amsterdam. Each subject provided a sample of blood which was assayed to measure testosterone concentrations. Correlations of testosterone in monozygotic twins were higher than in dizygotic twins. No resemblance was found between testosterone values in fathers and those in their children and a moderate correlation was seen between mothers and their daughters. The lack of resemblance between family members of opposite sex suggests that different genetic factors influence plasma testosterone concentrations in men and women. In adolescent men, approximately 60% of the variance in testosterone levels is heritable. The lack of father–son resemblance suggests that different genetic factors may be expressed in adolescence and adulthood. In women, 40% of the variance in testosterone levels is heritable, both in adolescence and in adulthood.

Testosterone genetics twins families sex differences 

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Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • Julie Aitken Harris
    • 1
  • Philip A. Vernon
    • 2
  • Dorret I. Boomsma
    • 3
  1. 1.Department of PsychologyThe University of Western OntarioLondonCanada
  2. 2.Department of PsychologyThe University of Western OntarioLondonCanada
  3. 3.Department of Psychology, De Boelelaan 1111Vrije UniversiteitAmsterdamThe Netherlands

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