Bulletin of Experimental Biology and Medicine

, Volume 134, Issue 2, pp 156–158 | Cite as

Effects of Horseradish Root on Functional Activity of Phagocytes, Total Blood Cell Count, and State of the Liver in Mice with Experimental Leprosy

  • A. K. Maslov
  • S. A. Luzhnova
  • O. V. Kalyanina
Article

Abstract

Therapy of experimental leprosy with dried and grated horseradish root administered perorally in a dose of 300 mg/kg mixed food and treatment with purified horseradish peroxidase increased myeloperoxidase activity of blood neutrophils, enhanced antimicrobial functions of phagocytes, decreased leukocytosis, normalized total blood cell count, and produced no adverse effects on the functional state of the liver in mice.

experimental leprosy horseradish root dynamics of M. leprae reproduction phagocyte activity hemogram 

REFERENCES

  1. 1.
    N. I. Bakhov, L. Z. Aleksandrova, and V. N. Titov, Lab. Delo, No. 6, 3–12 (1988).Google Scholar
  2. 2.
    Laboratory Studies in Clinical Practice, Ed. V. V. Men'shikov [in Russian], Moscow (1987).Google Scholar
  3. 3.
    A. K. Maslov and O. V. Kalyanina, Byull. Eksp. Biol. Med., 129,No. 5, 571–573 (2000).Google Scholar
  4. 4.
    A. K. Maslov and S. A. Luzhnova, Ibid., 130,No. 7, 83–87 (2000).Google Scholar
  5. 5.
    A. K. Maslov, S. A. Luzhnova, and O. V. Kalyanina, Ibid., 132,No. 11, 551–553 (2001).Google Scholar
  6. 6.
    Laboratory Techniques for Leprosy, Geneva (1987).Google Scholar
  7. 7.
    C. C. Shepard, J. Exp. Med., 112, 445–454 (1960).Google Scholar
  8. 8.
    C. C. Shepard and D. H. McRae, Int. J. Lepr., 36, 78–82 (1968).Google Scholar

Copyright information

© Plenum Publishing Corporation 2002

Authors and Affiliations

  • A. K. Maslov
    • 1
  • S. A. Luzhnova
    • 1
  • O. V. Kalyanina
    • 1
  1. 1.Institute for LeprosyRussian Ministry of HealthAstrakhan

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