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Journal of Assisted Reproduction and Genetics

, Volume 16, Issue 8, pp 436–442 | Cite as

Assessment of the Dominant Abnormal Form Is Useful for Predicting the Outcome of Intracytoplasmic Sperm Injection in the Case of Severe Teratozoospermia

  • Yoshiko Osawa
  • Kou Sueoka
  • Soukichi Iwata
  • Masami Shinohara
  • Noriko Kobayashi
  • Nadaki Kuji
  • Yasunori Yoshimura
Article

Abstract

Purpose: Our purpose was to investigate the relation between the dominant sperm anomaly and sperm morphology and the outcome of intracytoplasmic sperm injection (ICSI).

Methods: Two hundred ninety-five patients who underwent a total of 181 cycles of in vitro fertilization (n = 168) and/or 217 cycles of ICSI (n = 177) between July 1995 and May 1997 at Keio University Hospital were investigated.

Results: The rates of fertilization and pregnancy were 63.3 and 27.8%, respectively, in ICSI cycles with ≤4% normal forms. When the percentage of strictly normal morphology was ≤4, the fertilization rate was lower in the case of severely tapered head (13.0%; n = 4) than in the cases of other deformities in ICSI. The acrosomal defect made no difference in the fertilization rate with ICSI.

Conclusions: The predominant abnormal form affects the ICSI outcome in the case of ≤4% normal forms.

intracytoplasmic sperm injection morphology outcome teratozoospermia 

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Copyright information

© Plenum Publishing Corporation 1999

Authors and Affiliations

  • Yoshiko Osawa
    • 1
  • Kou Sueoka
    • 1
  • Soukichi Iwata
    • 1
  • Masami Shinohara
    • 1
  • Noriko Kobayashi
    • 1
  • Nadaki Kuji
    • 1
  • Yasunori Yoshimura
    • 1
  1. 1.Department of Obstetrics and GynecologyKeio University School of MedicineTokyoJapan

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