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Pharmaceutical Research

, Volume 19, Issue 10, pp 1577–1580 | Cite as

Monitoring the Penetration Enhancer Dimethyl Sulfoxide in Human Stratum Corneum in Vivo by Confocal Raman Spectroscopy

  • Peter J. Caspers
  • Adrian C. Williams
  • Elizabeth A. Carter
  • Howell G. M. Edwards
  • Brian W. Barry
  • Hajo A. Bruining
  • Gerwin J. Puppels
Article
penetration enhancer dimethyl sulfoxide human stratum corneum confocal Raman spectroscopy 

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REFERENCES

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    B. W. Barry. Dermatological Formulations, Percutaneous Absorption. Marcel Dekker, Inc., New York, 1983.Google Scholar
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    H. H. Szmant. Chemistry of DMSO. In S. W. Jacob, E. E. Rosenbaum, and D.C. Wood (eds.), Dimethyl Sulfoxide.Vol.1, Basic Concepts of DMSO. Marcel Dekker Inc., New York, 1971. 1-98.Google Scholar
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    B. W. Barry. Mode of action of penetration enhancers in human skin. J.Control.Release 6:85-97 (1987).Google Scholar
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    R. Wolthuis, T. C. Bakker Schut, P. J. Caspers, H. P. J. Buschman, T. J. Roemer, H. A. Bruining, and G. J. Puppels. In W. Mason (ed.), Fluorescent and Luminescent Probes for Biologic activity, Academic Press, London, 1999. 433-455.Google Scholar
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    A. N. C. Anigbogu, A. C. Williams, B. W. Barry, and H. G. M. Edwards. Fourier transform Raman spectroscopy of interactions between the penetration enhancer dimethyl sulfoxide and human stratum corneum. Int.J.Pharm. 125:265-282 (1995).Google Scholar

Copyright information

© Plenum Publishing Corporation 2002

Authors and Affiliations

  • Peter J. Caspers
    • 1
  • Adrian C. Williams
    • 2
  • Elizabeth A. Carter
    • 1
  • Howell G. M. Edwards
    • 3
  • Brian W. Barry
    • 1
  • Hajo A. Bruining
    • 2
  • Gerwin J. Puppels
    • 2
  1. 1.Laboratory for Intensive Care Research and Optical Spectroscopy, Department of General Surgery, 10M Faculty of Medicine and Health SciencesErasmus University Rotterdam and University Hospital RotterdamGD RotterdamThe Netherlands
  2. 2.Drug Delivery Group, School of PharmacyUniversity of BradfordWest YorkshireUnited Kingdom
  3. 3.Department of Chemical and Forensic SciencesUniversity of BradfordWest YorkshireUnited Kingdom

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