Digestive Diseases and Sciences

, Volume 47, Issue 9, pp 1921–1925 | Cite as

CASE REPORT: Fatal Progressive Hepatic Necrosis Associated with Lamotrigine Treatment: A Case Report and Literature Review

  • Kerith Overstreet
  • Christopher Costanza
  • Cynthia Behling
  • Tarrek Hassanin
  • Eliezer Masliah
Article
liver drug toxicity lamotrigine hepatotoxin 

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REFERENCES

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    Schaub N, Bircher AJ: Severe Hypersensitivity syndrome to lamotrigine confirmed by lymphocyte stimulation in vitro. Allergy 55:191–193, 2000Google Scholar
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    Makin AJ, Fitt S, Williams R, Duncan JS: Fulminant hepatic failure induced by lamotrigine. BMJ 311:292, 1995Google Scholar
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    Arnon R, DeVivo D, Defelice AR, Kazlow PG: Acute hepatic failure in a child treated with lamotrigine. Pediatr Neurol 18:251–252, 1998Google Scholar
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    Yuen AWC, Bihari DJ: Multiorgan failure and disseminated intravascular coagulation in severe convulsive seizures. The Lancet 340:618, 1992Google Scholar

Copyright information

© Plenum Publishing Corporation 2002

Authors and Affiliations

  • Kerith Overstreet
    • 1
  • Christopher Costanza
    • 2
  • Cynthia Behling
    • 1
  • Tarrek Hassanin
    • 2
  • Eliezer Masliah
    • 1
  1. 1.Department of PathologyUniversity of California San DiegoLa JollaUSA
  2. 2.Department of Medicine, Gastroenterology/Hepatology DivisionUniversity of California, San Diego Medical CenterSan DiegoUSA

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