Digestive Diseases and Sciences

, Volume 42, Issue 7, pp 1331–1343

What Can Be Measured from Surface Electrogastrography (Computer Simulations)

  • Jie Liang
  • J.D.Z. Chen
Article

Abstract

The aims of this study were to investigate thedetectability of the propagation of the gastric slowwave from the cutaneous electrogastrogram (EGG) and thepatterns of the EGG when the gastric slow waves are uncoupled. A mathematical model wasestablished based on the volume conductor theory tosimulate the transfer of the serosal gastric slow wavefrom the stomach to the abdominal surface. A number of computer simulations were conducted using themodel, and the periodic cross-correlation function wasused to estimate the phase shift between the fourchannels. It was found that the propagation of the gastric slow wave was detectable from themultichannel EGG signals. The detectability of thepropagation was, however, associated with a number offactors, such as the thickness of the abdominal wall and the propagation velocity of the serosal slowwave. The amplitude of the EGG was found to beassociated with the coupling/uncoupling and propagationvelocity of the gastric slow wave. The amplitude of the EGG increased when the propagation velocity ofthe gastric slow wave increased. The amplitude of theEGG was substantially decreased when the gastric slowwaves were uncoupled. The uncoupling of the gastric slow wave at a frequency of 3 cpm produceddysrhythmias in the EGG, including tachygastria,bradygastria, and arrhythmia. The power spectra ofsimulated different positional EGG signals showedsimilar patterns when the gastric slow wave was coupled anddifferent and unpredictable patterns when the gastricslow wave was uncoupled. In conclusion, multichannel EGGrecordings may be necessary to obtain more information on gastric slow waves from the abdominalelectrodes. The propagation and coupling or uncouplingof the gastric slow wave may be detected frommultichannel EGG recordings.

ELECTROGASTROGRAPHY MATHEMATICAL MODEL COMPUTER SIMULATION GASTROINTESTINAL MOTILITY GASTRIC EMPTYING 

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REFERENCES

  1. 1.
    Alvarez WC: The electrogastrogram and what it shows. JAMA 78:1116–1118, 1992Google Scholar
  2. 2.
    Abell TL, Malagelada J-R: Electrogastrography: Current assessments and future perspective. Dig Dis Sci 83:806–811, 1988Google Scholar
  3. 3.
    Chen J, Pan J, McCallum R W: Clinical significance of gastric myoelectrical dysrhythmias. Dig Dis 13:275–290, 1995Google Scholar
  4. 4.
    Chen J, McCallum R W: Clinical applications of electrogastrogram. Am J Gastroenterol 88:1324–1336, 1993Google Scholar
  5. 5.
    Dubois A: Gastric dysrhythmias: Pathophysiological and etiologic factors. Mayo Clin Proc 64:246–250, 1989Google Scholar
  6. 6.
    Geldof H, van der Schee EJ, Van Blankenstein M, Grashius JL: Electrogastrographic study of gastric myoelectrical activity in patients with unexplained nausea and vomiting. Gut 26:799–808, 1986Google Scholar
  7. 7.
    Kim CH, Zinsmeister AR, Malagelada JR: Effect of gastric dysrhythmias on postcibal motor activity of the stomach. Dig Dis Sci 33:193–199, 1988Google Scholar
  8. 8.
    Koch KL: Gastric dysrhythmias and the current status of electrogastrography. Pract Gastroenterol 13(4):37–44, 1989Google Scholar
  9. 9.
    Stern RM, Koch KL, Stewart WR, Vasey MW: Electrogastrography: Current issues in validation and methodology. Psychophysiol 24:55–64, 1987Google Scholar
  10. 10.
    Smout AJPM, van der Schee EJ, Grashuis JL: What is measured in electrogastrography? Dig Dis Sci 25:179–187, 1980Google Scholar
  11. 11.
    Familoni BO, Bowes KL, Kingma YJ, Cote KR: Can transcutaneous recordings detect gastric electrical abnormalities? Gut 32:141–146, 1991Google Scholar
  12. 12.
    Chen J, Schirmer BD, McCallum RW: Serosal and cutaneous recordings of gastric myoelectrical activity in patients with gastroparesis. Am J Physiol 266:G90–G98, 1994Google Scholar
  13. 13.
    El-Sharkawy TY, et al: Intracellular electrical activity of canine and human gastric smooth muscle. J Physiol 279:291–307, 1978Google Scholar
  14. 14.
    Mintchev MP, Bowes KL: Do increased electrogastrogram frequencies always correspond to internal tachygastria? Ann Biomed Eng (in press)Google Scholar
  15. 15.
    Desvarannes SB, Mizrahi M, Dubois A: Relation between postprandial gastric emptying and cutaneous electrogastrogram in primates. Am J Physiol 261:G248–G255, 1991Google Scholar
  16. 16.
    Chen J, Vandewalle J, Sansen W, van Cutsen E, Vantrappen G, Janssens J: Observation of the propagation direction of human electrogastric activity from cutaneous recordings. Med Biol Eng Comput 27:538–542, 1989Google Scholar
  17. 17.
    Daniel EE: Electrical and contractile activity of pyloric region in dogs and effects of drugs administered intra-arterially. Gastroenterology 49:403–418, 1965Google Scholar
  18. 18.
    Kelly K, Code CF: Effect of transthoracic vagotomy on canine electrical activity. Gastroenterology 55:51–58, 1969Google Scholar
  19. 19.
    Sarna SK: Simulation of the electrical control activity of the stomach by an array of relaxation oscillations. Dig Dis 17:299–310, 1972Google Scholar
  20. 20.
    Koch KL, Stern RM: The relationship between the cutaneously recorded electrogastrogram and antral contractions in man. In Electrogastrography. RM Stern, KL Koch (eds). New York, Praeger, 1985, pp 116–131Google Scholar
  21. 21.
    Plonsey R, Fleming D: Bioelectric Phenomena. New York, McGraw-Hill, 1969Google Scholar
  22. 22.
    Schuwan HP, Kay CF: The conductivity of living tissues. Ann NY Acad Sci 65:1007, 1957Google Scholar
  23. 23.
    Plonsey R, Collin R: Principles and Applications of Electromagnetic Fields. New York, McGraw-Hill, 1961Google Scholar
  24. 24.
    Rush S, et al: Resistivity of body tissues at low frequencies. Circ Res 12:40, 1963Google Scholar
  25. 25.
    Chen J, Yi XB, Schirmer BD, Schmieg R, McCallum RW: Impaired propagation of gastric slow waves in gastroparesis and the postoperative period. Gastroenterology 106:A477, 1994Google Scholar
  26. 26.
    Chen J, McCallum RW (eds): Electrogastrography: Principles and Applications. New York, Raven Press, 1994Google Scholar
  27. 27.
    Cucchiara S, Minella R, Riezzo G, Vallone G, Vallone P, Castellone F, Auricchio S: Reversal of gastric electrical dysrhythmias by cisapride in children with functional dyspepsia. Dig Dis Sci 37:1136–1140, 1992Google Scholar
  28. 28.
    Geldof H, van der Schee EJ, Grashuis JL: Electrogastrographic characteristics of interdigestive migrating complex in humans. Am J Physiol 250:G165–G171, 1986Google Scholar
  29. 29.
    Chen J, Lin ZY, Pan J, McCallum RW: Abnormal gastric myoelectrical activity and delayed gastric emptying in patients with symptoms suggestive of gastroparesis. Dig Dis Sci 41(8):1538–1545, 1996Google Scholar
  30. 30.
    Mirizzi N, Stella R, Scafoglieri U: A model of extracellular waveshapes of gastric electrical activity. Med Biol Eng Comput 23:33–37, 1985Google Scholar
  31. 31.
    Familoni BO, Abell TL, Bowes KL: A model of gastric electrical activity in health and disease. IEEE Trans on Biomed Eng 42(7):647–657, 1995Google Scholar
  32. 32.
    Kothapalli B: Electrogastrogram simulation using a three-dimensional model. Med Biol Eng Comp 31(5):482–486, 1993Google Scholar
  33. 33.
    Linkens DA: Electronic modeling of slow-waves and spike-activity in intestinal tissue. IEEE Trans Biomed Eng 27(7):351–357, 1980Google Scholar
  34. 34.
    Chen J, McCallum RW: Electrogastrogram: Measurement, analysis and prospective applications. Med Biol Eng Comput 29:339–350, 1991Google Scholar
  35. 35.
    Mirizzi N, Scafoglieri U: Optimal direction of the electrogastrographic signal in man. Med Biol Eng Comput 21:385–389, 1983Google Scholar

Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • Jie Liang
  • J.D.Z. Chen

There are no affiliations available

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