Digestive Diseases and Sciences

, Volume 43, Issue 9, pp 1991–1997

Gastroesophageal Reflux Disease Is a Common Cause of Noncardiac Chest Pain in a Country with a Low Prevalence of Reflux Esophagitis

  • Khek Yu Ho
  • Wai Lin Ng
  • Jin Yong Kang
  • Khay Guan Yeoh
Article

DOI: 10.1023/A:1018842811123

Cite this article as:
Ho, K.Y., Ng, W.L., Kang, J.Y. et al. Dig Dis Sci (1998) 43: 1991. doi:10.1023/A:1018842811123

Abstract

Gastroesophageal reflux disease is believed tobe uncommon in the East. This study aimed to determineif such a condition was a significant cause ofnoncardiac chest pain in Singapore. Eighty consecutive patients with recurrent chest pain, who hadcardiac and other obvious causes excluded, underwentesophagogastroduodenoscopy, standard manometry, acidperfusion test, and prolonged ambulatory pH and pressure monitoring. Endoscopic esophagitis, positiveacid perfusion tests, pathologic reflux, and positivechest pain-reflux correlation were detected in 7/80(8.8%), 11/70 (15.7%), 14/61 (23.0%), and 12/25 (48.0%) patients, respectively. Among thosewith pathologic reflux, endoscopic esophagitis waspresent in only two (14.3%). Overall, 32 (40%) patientshad gastroesophageal reflux disease. Esophageal motility disorder, alone or in association withgastroesophageal reflux disease, was demonstrated inonly five (6.3%) patients. Our results confirmed westernreports that gastroesophageal reflux disease was a common cause of noncardiac chest pain,whereas motility disorder was an infrequent cause ofsuch pain.

NONCARDIAC CHEST PAIN GASTROESOPHAGEAL REFLUX DISEASE ESOPHAGEAL MOTILITY DISORDER ESOPHAGEAL pH RECORDING ESOPHAGEAL PRESSURE RECORDING SYMPTOM ANALYSIS 

Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • Khek Yu Ho
  • Wai Lin Ng
  • Jin Yong Kang
  • Khay Guan Yeoh

There are no affiliations available

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