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Ecotoxicology

, Volume 6, Issue 1, pp 35–65 | Cite as

Chemical contamination and associated liver diseases in two species of fish from San Francisco Bay and Bodega Bay

  • CARLA M. Stehr
  • MARK S. Myers
  • DOUGLAS G. BURROWS
  • MARGARET M. Krahn
  • JAMES P. Meador
  • BRUCE B. McCAIN
  • USHA Varanasi
Article

Abstract

Starry flounder (Platichthys stellatus), white croaker (Genyonemus lineatus) and sediments were collected annually from selected sites within San Francisco Bay, and a reference site in Bodega Bay between 1984--1991. Fish livers were examined for toxicopathic lesions and analysed for selected chlorinated hydrocarbons (CHs) such as PCBs, DDTs, chlordanes and dieldrin; sediment and fish stomach contents were analysed for polycyclic aromatic hydrocarbons (PAHs) and CHs; and bile was analysed for PAH metabolites. Sediment concentrations of PAHs, PCBs and DDTs; bile concentrations of PAH metabolites; and liver concentrations of PCBs, dieldrin and chlordanes were generally significantly higher at all San Francisco Bay sites compared to the Bodega Bay reference site. For both species, hydropic vacuolation of biliary epithelial cells was the most prevalent liver lesion detected and was statistically associated with sediment and tissue concentrations of PAHs or their metabolites, PCBs, DDTs, chlordanes and dieldrin. Temporal trends analyses showed that at Hunters Point, sediment PAHs and CHs increased between 1984--1991, while liver concentrations of CHs decreased. Liver concentrations of dieldrin in starry flounder decreased at all three San Francisco Bay sites

chemicalpollution fish sediment San Francisco Bay liver diseases 

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Copyright information

© Chapman and Hall 1997

Authors and Affiliations

  • CARLA M. Stehr
    • 1
  • MARK S. Myers
    • 1
  • DOUGLAS G. BURROWS
    • 1
  • MARGARET M. Krahn
    • 1
  • JAMES P. Meador
    • 1
  • BRUCE B. McCAIN
    • 1
  • USHA Varanasi
    • 1
  1. 1.Environmental Conservation Division, Northwest Fisheries Science Center, National Marine Fisheries ServiceNational Oceanic and Atmospheric AdministrationSeattleUSA

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