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Bulletin of Experimental Biology and Medicine

, Volume 133, Issue 4, pp 384–385 | Cite as

Pine Resin and Biopin Ointment: Immunotoxic and Allergenic Activity

  • A. S. Simbirtsev
  • V. G. Konusova
  • G. Sh. Mchedlidze
  • E. Z. Fidarov
  • B. A. Paramonov
  • V. Yu. ChebotarevEmail author
Article

Abstract

We studied properties of ointment Biopin containing pine resin and used for the therapy of burns, wounds, and purulent and inflammatory diseases. Long-term treatment with this preparation in clinical doses had no effect on the nonspecific, but modulated the specific immune response. Biopin ointment inhibited humoral, but stimulated cell immunity. Neither local irritation, nor allergic reactions were found after long-term epicutaneous application of the preparation.

pine resin Biopin ointment nonspecific immunity specific immunity allergic effect 

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Copyright information

© Plenum Publishing Corporation 2002

Authors and Affiliations

  • A. S. Simbirtsev
    • 1
  • V. G. Konusova
    • 1
  • G. Sh. Mchedlidze
    • 1
  • E. Z. Fidarov
    • 1
  • B. A. Paramonov
    • 1
  • V. Yu. Chebotarev
    • 1
    Email author
  1. 1.Institute of High-Purity Biological PreparationsSt. Petersburg-TechnologySt. Petersburg

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