Digestive Diseases and Sciences

, Volume 47, Issue 7, pp 1590–1593 | Cite as

CASE REPORT: Vagus Nerve Injury with Severe Diarrhea After Laparoscopic Antireflux Surgery

  • Andrzej Ukleja
  • Timothy A. Woodward
  • Sami R. Achem
denervation, autonomic diarrhea reflux, gastroesophageal surgery, laparoscopic vagotomy vagus nerve 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Dallemagne B, Weerts JM, Jehaes C, Markiewicz S: Results of laparoscopic Nissen fundoplication. Hepatogastroenterology 45:1338–1343, 1998Google Scholar
  2. 2.
    Dallemagne B, Weerts JM, Jehaes C, Markiewicz S, Lombard R: Laparoscopic Nissen fundoplication: Preliminary report. Surg Laparosc Endosc 1:138–143, 1991Google Scholar
  3. 3.
    Hinder RA, Filipi CJ, Wetscher G, Neary P, DeMeester TR, Perdikis G: Laparoscopic Nissen fundoplication is an effective treatment for gastroesophageal reflux disease. Ann Surg 220:472–481, 1994Google Scholar
  4. 4.
    Ferguson MK: Pitfalls and complications of antireflux surgery. Nissen and Collis-Nissen techniques. Chest Surg Clin N Am 7:489–511, 1997Google Scholar
  5. 5.
    Vansant JH, Baker JW Jr: Complications of vagotomy in the treatment of hiatal hernia. Ann Surg 183:629–635, 1976Google Scholar
  6. 6.
    Debas HT, Orloff SL: Surgery for peptic ulcer disease. In Textbook of Gastroenterology, Vol. 1. T Yamada, DH Alpers, C Owyang, DW Powell, FE Silverstein (eds). Philadelphia: Lippincott, 1991, pp 1379–1398Google Scholar
  7. 7.
    Kozarek RA, Low DE, Raltz SL: Complications associated with laparoscopic anti-reflux surgery: One multispecialty clinic's experience. Gastrointest Endosc 46:527–531, 1997Google Scholar
  8. 8.
    Trus TL, Bax T, Richardson WS, Branum GD, Mauren SJ, Swanstrom LL, Hunter JG: Complications of laparoscopic paraesophageal hernia repair. J Gastrointest Surg 1:221–228, 1997Google Scholar
  9. 9.
    Korman MG, Strickland RG, Hansky J: Serum gastrin in chronic gastritis. BMJ 2:16–18, 1971Google Scholar
  10. 10.
    Ganguli PC, Cullen DR, Irvine WJ: Radioimmunoassay of plasmagastrin in pernicious anaemia, achlorhydria without pernicious anaemia, hypochlorhydria, and in controls. Lancet 1:155–158, 1971Google Scholar
  11. 11.
    Engel JJ, Spellberg MA: Complications of vagotomy. Am J Gastroenterol 70:55–60, 1978Google Scholar
  12. 12.
    McKelvey ST: Gastric incontinence and post-vagotomy diarrhoea. Br J Surg 57:741–747, 1970Google Scholar
  13. 13.
    Ladas SD, Isaacs PE, Quereshi Y, Sladen G: Role of the small intestine in postvagotomy diarrhea. Gastroenterology 85:1088–1093, 1983Google Scholar
  14. 14.
    Thompson DG, Ritchie HD, Wingate DL: Patterns of small intestinal motility in duodenal ulcer patients before and after vagotomy. Gut 23:517–523, 1982Google Scholar
  15. 15.
    Blake G, Kennedy TL, McKelvey ST: Bile acids and postvagotomy diarrhoea. Br J Surg 70:177–179, 1983Google Scholar
  16. 16.
    Condon JR, Robinson V, Suleman MI, Fan VS, McKeown MD: The cause and treatment of postvagotomy diarrhoea. Br J Surg 62:309–312, 1975Google Scholar
  17. 17.
    Dragstedt LR, Woodward ER: Appraisal of vagotomy for peptic ulcer after seven years. JAMA 145:795–802, 1951Google Scholar
  18. 18.
    McColl I, Drinkwater JE, Hulme-Moir I, Donnan SP: Prediction of success or failure of gastric surgery. Br J Surg 58:768–771, 1971Google Scholar
  19. 19.
    Hunter JG, Trus TL, Branum GD, Waring JP, Wood WC: A physiologic approach to laparoscopic fundoplication for gastroesophageal reflux disease. Ann Surg 223:673–685, 1996Google Scholar
  20. 20.
    Hunter RJ, Metz DC, Morris JB, Rothstein RD: Gastroparesis: a potential pitfall of laparoscopic Nissen fundoplication. Am J Gastroenterol 91:2617–2618, 1996Google Scholar
  21. 21.
    Urschel JD: Complications of antireflux surgery. Am J Surg 166:68–70, 1993Google Scholar
  22. 22.
    Luostarinen M: Nissen fundoplication for reflux esophagitis. Long-term clinical and endoscopic results in 109 of 127 consecutive patients. Ann Surg 217:329–337, 1993Google Scholar
  23. 23.
    Bittner HB, Meyers WC, Brazer SR, Pappas TN: Laparoscopic Nissen fundoplication: Operative results and short-term follow-up. Am J Surg 167:193–198, 1994Google Scholar
  24. 24.
    Jamieson GG, Watson DI, Britten-Jones R, Mitchell PC, Anvari M: Laparoscopic Nissen fundoplication. Ann Surg 220:137–145, 1994Google Scholar
  25. 25.
    Collard JM, de Gheldere CA, De Kock M, Otte JB, Kestens PJ: Laparoscopic antireflux surgery. What is real progress? Ann Surg 220:146–154, 1994Google Scholar
  26. 26.
    Swanstrom L, Wayne R: Spectrum of gastrointestinal symptoms after laparoscopic fundoplication. Am J Surg 167:538–541, 1994Google Scholar
  27. 27.
    Aye RW, Hill LD, Kraemer SJ, Snopkowski P: Early results with the laparoscopic Hill repair. Am J Surg 167:542–546, 1994Google Scholar
  28. 28.
    Peters JH, Heimbucher J, Kauer WK, Incarbone R, Bremner CG, DeMeester TR: Clinical and physiologic comparison of laparoscopic and open Nissen fundoplication. J Am Coll Surg 180:385–393, 1995Google Scholar
  29. 29.
    Perdikis G, Hinder RA, Lund RJ, Raiser F, Katada N: Laparoscopic Nissen fundoplication: Where do we stand? Surg Laparosc Endosc 7:17–21, 1997Google Scholar
  30. 30.
    Stein HJ, Feussner H, Siewert JR: Failure of antireflux surgery: Causes and management strategies. Am J Surg 171:36–40, 1996Google Scholar
  31. 31.
    Chung SA, Greenberg GR, Diamant NE: Relationship of postprandial motilin, gastrin, and pancreatic polypeptide release to intestinal motility during vagal interruption. Can J Physiol Pharmacol 70:1148–1153, 1992Google Scholar
  32. 32.
    Schwartz TW, Stenquist B, Olbe L: Cephalic phase of pancreatic-polypeptide secretion studied by sham feeding in man. Scand J Gastroenterol 14:313–320, 1979Google Scholar
  33. 33.
    Glasbrenner B, Bruckel J, Gritzmann R, Adler G: Cephalic phase of pancreatic polypeptide release: A valid test of autonomic neuropathy in diabetics? Diabetes Res Clin Pract 30:117–123, 1995Google Scholar
  34. 34.
    Lieverse RJ, Masclee AA, Jansen JB, Lamers CB: Plasma cholecystokinin and pancreatic polypeptide secretion in response to bombesin, meal ingestion and modified sham feeding in lean and obese persons. Int J Obes Relat Metab Disord 18:123–127, 1994Google Scholar
  35. 35.
    Thirlby RC, Patterson DJ, Kozarek RA: Prospective comparison of congo red and sham feeding testing to determine vagal innervation of the stomach. Am J Surg 163:533–536, 1992Google Scholar
  36. 36.
    Kusakari K, Nyhus LM, Gillison EW, Bombeck CT: An endoscopic test for completeness of vagotomy. Arch Surg 105:386–391, 1972Google Scholar
  37. 37.
    Saik RP, Greenburg AG, Peskin GW: The Congo red test to determine completeness of vagotomy: clinical application. Am J Surg 144:518–522, 1982Google Scholar
  38. 38.
    Allan JG, Russell RI: Cholestyramine in treatment of postvagotomy diarrhoea—Double-blind controlled trial. BMJ 1:674–676, 1977Google Scholar
  39. 39.
    Herrington JL Jr, Edwards WH, Carter JH, Sawyers JL: Treatment of severe postvagotomy diarrhea by reversed jejunal segment. Ann Surg 168:522–541, 1968Google Scholar
  40. 40.
    Herrington JL Jr, Sawyers JL: A new operation for the dumping syndrome and post-vagotomy diarrhea. Ann Surg 175:790–801, 1972Google Scholar

Copyright information

© Plenum Publishing Corporation 2002

Authors and Affiliations

  • Andrzej Ukleja
    • 1
  • Timothy A. Woodward
    • 1
  • Sami R. Achem
    • 1
  1. 1.Division of Gastroenterology and HepatologyMayo ClinicJacksonvilleUSA

Personalised recommendations