European Journal of Epidemiology

, Volume 17, Issue 9, pp 891–896

Seroprevalence of Borrelia burgdorferi in Romania

  • Adriana Hristea
  • Sanda Hristescu
  • Constantin Ciufecu
  • Adriana Vasile
Article

Abstract

In order to assess the seroprevalence of Borrelia burgdorferi in Romania and to define associated risk factors, a cross-sectional, observational study was performed in 13 districts during 1999. Sera from healthy blood donors (1598) and from forestry workers (1048) were tested. A two-step testing strategy was used in which sera were tested for anti-B. burgdorferi antibodies by a commercially available passive hemagglutination assays (PHA). All PHA positive sera were then evaluated by Western blot IgG. Demographic data regarding age, sex, profession, work place/residence, duration of employment (forestry workers), animals in the environment, and tick bites history were collected using a questionnaire. Data obtained from serological study were matched with that obtained from the questionnaire. The seroprevalence of B. burgdorferi in blood donors was of 4.3% (range 1.4–8.7%) and 9.3% (range 2.8–31.7%) in forestry workers. Seroprevalence was higher in forestry workers with a tick bite history (10.7 vs. 4.3%, p < 0.05). The highest seroprevalence in blood donors (8.7%) was noted in Maramures, a northern district of the country, whereas in forestry workers the highest seroprevalence (31.7%) was observed in a western district (Arad), where a previous study in entomology has demonstrated the highest density of Ixodes ricinus ticks in Romania.

Asymptomatic infection Borrelia burgdorferi Romania Seroprevalence 

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Copyright information

© Kluwer Academic Publishers 2001

Authors and Affiliations

  • Adriana Hristea
    • 1
  • Sanda Hristescu
    • 2
  • Constantin Ciufecu
    • 2
    • 3
  • Adriana Vasile
    • 4
  1. 1.Infectious Diseases Department, Institute of Infectious Diseases ‘Prof Dr Matei Bals’University of Medicine and Pharmacy ‘Carol Davila’BucharestRomania
  2. 2.Institute of Microbiology ‘Cantacuzino’Romania
  3. 3.Department of EpidemiologyUniversity of Medicine and Pharmacy ‘Carol Davila’BucharestRomania
  4. 4.Department of Public Health and ManagementUniversity of Medicine and Pharmacy ‘Carol Davila’Bucharest, BucurestiRomania

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