, Volume 153, Issue 1, pp 11–14 | Cite as

Mycetoma caused by Fusarium solani with osteolytic lesions on the hand: case report

  • Jane Tomimori-Yamashita
  • Marília M. Ogawa
  • Sérgio H. Hirata
  • Olga Fischman
  • Nílceo S. Michalany
  • Hélio Kiitiro Yamashita
  • Maurício M.A. Alchorne


Eumycetoma is a mycotic disease caused by saprophytic soil fungi that are usually inoculated through minor injuries. A case of mycetoma in a Brazilian farmer aged71 years is reported. This patient presented erythema and edema on the dorsal surface of the left hand with multiple crusted and cicatricial lesions. No macroscopic grains were observed. The histopathological findings showed grains consisted of numerous hyphae which stained well with Gomori-Grocott method. This material obtained by cutaneous biopsy was submitted to culture on Sabouraud’s medium and the colonies were identified as Fusarium solani. The radiological studies revealed bone osteolytic lesions and the ultrasound showed pseudocysts and fistulae at the site of this infection. The patient was treated with oral ketoconazole with a good clinical response.

Bone Eumycetoma Fusarium solani Hand 


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  1. 1.
    Buiting AG, Visser LG, Barge RM, Van'tWout JW.Mycetoom van de voet; een ziekte uit de tropen. Ned Tijdschr Geneeskd 1993; 137: 1513–1515.PubMedGoogle Scholar
  2. 2.
    Crissey JT, Lang H, Parish LC. Miscellaneous mycotic and pseudomycotic diseases. In: Crissey JT, Lang H, Parish LC, eds. Manual of medical mycology. Massachusetts: Blackwell Science, 1995: 203–225.Google Scholar
  3. 3.
    Rippon JW. Fusarium spp. In: Rippon JW, ed. Medical Mycology. 3rd ed. Philadelphia: W.B. Sauders Company, 1988: 732–735.Google Scholar
  4. 4.
    Zapater RC. Consideraciones sobre las micosis oculares. Rev Arg Micología 1983; 6: 31–32.Google Scholar
  5. 5.
    Luque AG, Ramos LL, Amigot SL. Onicomicosis producida por Fusarium solani. Rev Arg Micología 1989; 81: 22–24.Google Scholar
  6. 6.
    Gupta AK, Elewski BE. Nondermatophyte causes of onychomycosis and superficial mycoses. Curr Top Med Mycol 1996; 17: 87–97.Google Scholar
  7. 7.
    Gianni C, Cerri A, Crosti C. Unusual clinical features of fingernail infection by Fusarium oxysporum. Mycoses 1997; 40: 455–459.PubMedCrossRefGoogle Scholar
  8. 8.
    Shaoxi W, Ningro G, Guixia, L. A rare case of Fusarium verticillioides facial granuloma successfully treated by itraconazole. J Mycol Med 1996; 6: 88–90.Google Scholar
  9. 9.
    Destombes P, Mariat F, Rosati L, Segretain G. Mycetoma in Somalia — results of a survey done from 1959 to 1964. Acta Trop 1977; 34: 355–373.PubMedGoogle Scholar
  10. 10.
    Thianprasit M, Sivayathorn A. Black dot mycetoma. Mykosen 1984; 27: 219–226.PubMedGoogle Scholar
  11. 11.
    Luque AG, Mujica MT, D'Anna ML, Alvarez DP. Micetoma podal por Fusarium solani. Bol Micol (Valparaiso) 1991; 6: 55–57.Google Scholar
  12. 12.
    Baudraz-Rosselet F, Monod M, Borradori L, et al. Mycetoma of the foot due to Fusarium sp. Treated with oral ketoconazole. Dermatology 1992; 184: 303–305.PubMedCrossRefGoogle Scholar
  13. 13.
    Ochoa MT, Franco L, Restrepo O, et al. Um caso de eumicetoma por Fusarium oxysporum y su tratamiento com itraconazol. Rev Soc Col Dermatol 1992; 1: 93–95.Google Scholar
  14. 14.
    De Hoog GS, Buiting A, Tan CS, et al. Diagnostic problems with imported cases of mycetoma in The Netherlands. Mycoses 1993; 36: 81–87.PubMedCrossRefGoogle Scholar
  15. 15.
    Resnik BI, Burdick AE. Improvement of eumycetoma with itraconazole. J Am Acad Dermatol 1995; 33: 917–919.PubMedCrossRefGoogle Scholar

Copyright information

© Kluwer Academic Publishers 2002

Authors and Affiliations

  • Jane Tomimori-Yamashita
    • 1
  • Marília M. Ogawa
    • 1
  • Sérgio H. Hirata
    • 1
  • Olga Fischman
    • 2
  • Nílceo S. Michalany
    • 3
  • Hélio Kiitiro Yamashita
    • 4
  • Maurício M.A. Alchorne
    • 1
  1. 1.Departments of Dermatology, Cellular BiologyFederal University of São Paulo (UNIFESP-EPM)São PauloBrazil
  2. 2.Departments of Dermatology, ImagingFederal University of São Paulo (UNIFESP-EPM)São PauloBrazil
  3. 3.Federal University of São Paulo (UNIFESP-EPM)São PauloBrazil
  4. 4.Departments of Dermatology, and PathologyFederal University of São Paulo (UNIFESP-EPM)São PauloBrazil

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