Cancer Causes & Control

, Volume 13, Issue 4, pp 317–324 | Cite as

Cancer incidence in California flight attendants (United States)

  • Peggy Reynolds
  • James Cone
  • Michael Layefsky
  • Debbie E. Goldberg
  • Susan Hurley

Abstract

Objective: To examine unusual exposure opportunities to flight crews from chemicals, cosmic radiation, and electric and magnetic fields. Methods: This project evaluated the incidence of cancers of the breast and other sites among Association of Flight Attendants (AFA) members residing in California. AFA membership files were matched to California's statewide cancer registry to identify a total of 129 newly diagnosed invasive cancers among AFA members with California residential histories between 1988 and 1995. Results: Compared to the general population, female breast cancer incidence was over 30% higher than expected, and malignant melanoma incidence was roughly twice that expected. Both of these are cancers that are associated with higher socioeconomic status and have been suggestively associated with various sources of radiation. Conclusions: Consistent with the results from Nordic studies of cabin crews and a recent meta-analysis of prior studies, these data suggest that follow-up investigations should focus on the potential relative contribution of workplace exposures and lifestyle characteristics to the higher rates of disease for these two cancers.

breast cancer cancer registry flight attendants malignant melanoma 

References

  1. 1.
    United States Congress, House Committee on Government Operations, Government Activities and Transportation Subcommittee (1980) FAA-OSHA jurisdiction over workplace safety in the aviation Cancer in California flight attendants 323 industry: Hearing before a subcommittee of the Committee on Government Operations, House of Representatives, 96th Congress, 2nd Session. (Statement of James M. Melius, Chief, Hazard Evaluations and Technical Assistance Branch-National Institute forOccupational Safety and Health.) Available from Washington, DC: US Government Printing Office, Govt Doc No. Y 4.G74/ 7:F31/37.Google Scholar
  2. 2.
    Haldorsen T, Reitan JB, Tveten U (2001) Cancer incidence among Norwegian airline cabin attendants. Int J Epidemiol 30: 825-830.Google Scholar
  3. 3.
    Pukkala E, Auvinen A, Wahlberg G (1995) Incidence of cancer among Finnish airline cabin attendants, 1967-92. BMJ 311: 649-652.Google Scholar
  4. 4.
    Lynge E (1996) Risk of breast cancer is also increased among Danish female airline cabin attendants. BMJ 312: 253.Google Scholar
  5. 5.
    Wartenberg D, Stapleton CP (1998) Risk of breast cancer is also increased among retired US female airline cabin attendants. BMJ 316: 1902.Google Scholar
  6. 6.
    Rafnsson V, Tulinius H, Jonasson JG, Hrafnkelsson J (2001) Risk of breast cancer in female flight attendants: a population-based study (Iceland). Cancer Causes Control 12: 95-101.Google Scholar
  7. 7.
    John EM, Kelsey JL (1993) Radiation and otherenvir onmental exposures and breast cancer. Epidemiol Rev 15: 157-162.Google Scholar
  8. 8.
    Jaro MA (1995) Probabilistic linkage of large public health data files. Stat Med 14: 491-498.Google Scholar
  9. 9.
    Perkins C, Morris C, Wright W (1996) Cancer incidence and mortality in California by race/ethnicity, 1988-1993. Sacrament, CA: California Department of Health Services, Cancer Surveillance Section.Google Scholar
  10. 10.
    Ulm K (1990) A simple method to calculate the confidence interval of a standardized mortality ratio (SMR). Am J Epidemiol 131: 373-375.Google Scholar
  11. 11.
    van derGulden JW, Verbeek AL (1992) Re: ''A simple method to calculate the confidence interval of a standardized mortality ratio (SMR)''. Am J Epidemiol 136: 1170-1172.Google Scholar
  12. 12.
    Band PR, Spinelli JJ, Ng VT, Moody J, Gallagher RP (1990) Mortality and cancer incidence in a cohort of commercial airline pilots. Aviat Space Environ Med 61: 299-302.Google Scholar
  13. 13.
    Salisbury DA, Band PR, Threlfall WJ, Gallagher RP (1991) Mortality among British Columbia pilots. Aviat Space Environ Med 62: 351-352.Google Scholar
  14. 14.
    Kaji M, Tango T, Asukata I, et al. (1993) Mortality experience of cockpit crewmembers from Japan Airlines. Aviat Space Environ Med 64: 748-750.Google Scholar
  15. 15.
    Band PR, Le ND, Fang R, et al. (1996) Cohort study of Air Canada pilots: mortality, cancer incidence, and leukemia risk. Am J Epidemiol 143: 137-143.Google Scholar
  16. 16.
    Grayson JK, Lyons TJ (1996) Cancer incidence in United States Air Force aircrew, 1975-89. Aviat Space Environ Med 67: 101-104.Google Scholar
  17. 17.
    Nicholas JS, Lackland DT, Dosemeci M, et al. (1998) Mortality among US commercial pilots and navigators. J Occup EnvironMed 40: 980-985.Google Scholar
  18. 18.
    Rafnsson V, Hrafnkelsson J, Tulinius H (2000) Incidence of cancer among commercial airline pilots. Occup Environ Med 57: 175-179.Google Scholar
  19. 19.
    Irvine D, Davies DM (1999) British Airways flightdeck mortality study, 1950-1992. Aviat Space Environ Med 70: 548-555.Google Scholar
  20. 20.
    Haldorsen T, Reitan JB, Tveten U (2000) Cancer incidence among Norwegian airline pilots. Scand J WorkEnviron Health 26: 106-111.Google Scholar
  21. 21.
    Ballard T, Lagorio S, De Angelis G, Verdecchia A (2000) Cancer incidence and mortality among flight personnel: a meta-analysis. Aviat Space Environ Med 71: 216-224.Google Scholar
  22. 22.
    Lynge E (2001) Commentary: Cancer in the air. Int J Epidemiol 30: 830-832.Google Scholar
  23. 23.
    Boice JD Jr, Blettner M, Auvinen A (2000) Epidemiologic studies of pilots and aircrew. Health Phys 79: 576-584.Google Scholar
  24. 24.
    US Department of Transportation Federal Aviation Administration (2000) Advisory circular-Radiation Exposure of Air Carrier Crewmembers. Washington, DC: US Department of Transportation, 90. Circular No. FAA AC 120-52 (available at: http:// ntl.bts.gov/DOCS/Ac12052.html).Google Scholar
  25. 25.
    Cardis E, Gilbert ES, Carpenter L, et al. (1995) Effects of low doses and low dose rates of external ionizing radiation: cancer mortality among nuclear industry workers in three countries. Radiat Res 142: 117-132.Google Scholar
  26. 26.
    Waters M, Bloom TF, Grajewski B (2000) The NIOSH/FAA Working Women's Health Study: evaluation of the cosmicradiation exposures of flight attendants. Federal Aviation Administration. Health Phys 79: 553-559.Google Scholar
  27. 27.
    Blettner M, Grosche B, Zeeb H (1998) Occupational cancer risk in pilots and flight attendants: current epidemiological knowledge. Radiat Environ Biophys 37: 75-80.Google Scholar

Copyright information

© Kluwer Academic Publishers 2002

Authors and Affiliations

  • Peggy Reynolds
    • 1
  • James Cone
    • 2
  • Michael Layefsky
    • 3
  • Debbie E. Goldberg
    • 3
  • Susan Hurley
    • 3
  1. 1.California Department of Health ServicesEnvironmental Health Investigations BranchOaklandUSA
  2. 2.California Department of Health ServicesOccupational Health BranchOaklandUSA
  3. 3.Public Health InstituteBerkeleyUSA

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