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Russian Journal of Genetics

, Volume 38, Issue 3, pp 309–314 | Cite as

Polymorphism of the Y-Chromosome Diallelic Loci in Ethnic Groups of the Altai–Sayan Region

  • M. V. Derenko
  • B. A. Malyarchuk
  • G. A. Denisova
  • Ch. M. Dorzhu
  • O. N. Karamchakova
  • F. A. Luzina
  • E. A. Lotosh
  • I. K. Dambueva
  • U. N. Ondar
  • I. A. Zakharov
Article

Abstract

Using the data on five diallellic Y-chromosome loci (DYS199,92R7, SRY1532, RBF5, and DYS287) polymorphism, genetic structures of the five Turkic-speaking ethnic groups of the Altai–Sayan upland (Tuvinians, Sojots, Shorians, Khakassians, and Southern Altaians (Altai-Kizhi), were described. The gene pools of the populations examined were characterized by the presence of pronounced paleo-Caucasoid component (92R7-T-lineages). The frequency of this component increased westward, reaching more than 70% in Shorians and Southern Altaians. Haplotype TAT-C (RBF5 locus) was observed in all populations, except Shorians, with the frequencies varying from 5.4% in Altai-Kizhi to 18.8% in Khakassians. The Alu-insertion in the DYS287 locus was revealed only in the Altaian sample with the frequency of 3.3%. It was established that the Altai–Sayan populations studied split into two statistically significantly different groups. One of the groups was represented by Tuvinians, Sojots, and Khakassians, while another one was comprised of Shorians and Altaians.

Keywords

Ethnic Group Genetic Structure Gene Pool Sayan Region Diallelic Locus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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REFERENCES

  1. 1.
    Alekseev, V.P. and Gokhman, I.I., Anthropology of the Asian Part of the USSR, Moscow: Nauka, 1984.Google Scholar
  2. 2.
    Narody Sibiri (Siberian Ethnoses), Levin, M.G. and Potapov, L.P., Eds., Moscow: Akad. Nauk SSSR, 1956.Google Scholar
  3. 3.
    Alekseev, V.P., Istoricheskaya antropologiya i antropo-genez (Historical Anthropology and Anthropogenesis), Moscow: Nauka, 1989Google Scholar
  4. 4.
    Jobling, M.A. and Tyler-Smith, C., Father and Sons: The Y Chromosome and Human Evolution, Trends Genet., 1995, vol. 11, pp. 449-456.Google Scholar
  5. 5.
    Underhill, P.A., Jin, L., and Lin, A.A., Detection of Numerous Y Chromosome Diallelic Polymorphisms by Denaturing High-Performance Liquid Chromatography, Genome Res., 1997, vol. 7, pp. 996-1005.Google Scholar
  6. 6.
    Hammer, M.F., A Recent Insertion of an Alu Element on the Y Chromosome Is a Useful Marker for Human Population Studies, Mol. Biol. Evol., 1994, vol. 11, pp. 749-761.Google Scholar
  7. 7.
    Santos, F., Pandya, A., Kayser, M., et al., A Polymorphic L1 Retroposon Insertion in the Centromere of the Human Y Chromosome, Hum. Mol. Genet., 2000, vol. 9, pp. 421-430.Google Scholar
  8. 8.
    Heyer, E., Puymirat, J., Dieltjes, P., et al., Estimating Y Chromosome-Specific Microsatellite Mutation Frequencies Using Deep Rooting Pedigrees, Hum. Mol. Genet., 1997, vol. 6, pp. 799-803.Google Scholar
  9. 9.
    Jobling, M.A., Bouzekri, N., and Taylor, P.G., Hyper-variable Digital DNA Codes for Human Paternal Lineages: MVR-PCR at the Y-Specific Minisatellite, MSY1 (DYF155S1), Hum. Mol. Genet., 1998, vol. 7, pp. 643-653.Google Scholar
  10. 10.
    Santos, F.R., Pandya, A., Tyler-Smith, C., et al., The Central Siberian Origin for Native American Y Chromosomes, Am. J. Hum. Genet., 1999, vol. 64, pp. 619-628.Google Scholar
  11. 11.
    Karafet, T.M., Zegura, S.L., Posukh, O., et al., Ancestral Asian Source(s) of New World Y-Chromosome Founder Haplotypes, Am. J. Hum. Genet., 1999, vol. 64, pp. 817-831.Google Scholar
  12. 12.
    Rosser, Z.H., Zerjal, T., Hurles, M., et al., Y-Chromosomal Diversity in Europe Is Clinal and Influenced Primarily by Geography, Rather Then by Language, Am. J. Hum. Genet., 2000, vol. 67, pp. 1526-1543.Google Scholar
  13. 13.
    Walsh, P.S., Metzger, D.A., and Higuchi, R., Research Report: Chelex 100 as a Medium for Simple Extraction of DNA for PCR-Based Typing from Forensic Material, BioTechniques, 1991, vol. 10, pp. 506-513.Google Scholar
  14. 14.
    Hammer, M.F. and Horai, S., Y-Chromosomal DNA Variation and the Peopling of Japan, Am. J. Hum. Genet., 1995, vol. 56, pp. 951-962.Google Scholar
  15. 15.
    Mathias, N., Bayes, M., and Tyler-Smith, C., Highly Informative Compound Haplotypes for the Human Y Chromosome, Hum. Mol. Genet., 1994, vol. 3, pp. 115-123.Google Scholar
  16. 16.
    Hurles, M.E., Veitia, R., Arroyo, E., et al., Recent Male-Mediated Gene Flow over a Linguistic Barrier in Iberia, Suggested by Analysis of a Y-Chromosomal DNA Polymorphism, Am. J. Hum. Genet., 1999, vol. 65, pp. 1437-1448.Google Scholar
  17. 17.
    Zerjal, T., Dashnyam, B., Pandya, A., et al., Genetic Relationships of Asians and Northern Europeans, Revealed by Y-Chromosome DNA Analysis, Am. J. Hum. Genet., 1997, vol. 60, pp. 1174-1183.Google Scholar
  18. 18.
    Underhill, P.A., Jin, L., Zemans, R., et al., A Pre-Columbian Y Chromosome-Specific Transition and Its Implications for Human Evolutionary History, Proc. Natl. Acad. Sci. USA, 1996, vol. 93, pp. 196-200.Google Scholar
  19. 19.
    Whitfield, L.S., Sulston, J.E., and Goodfellow, P.N., Sequence Variation of the Human Y-Chromosome, Nature, 1995, vol. 378, pp. 379-380.Google Scholar
  20. 20.
    Nei, M. and Tajima, F., DNA Polymorphism Detectable by Restriction Endonucleases, Genetics, 1981, vol. 97, pp. 145-163.Google Scholar
  21. 21.
    Zhivotovsky, L.A., Statistical Methods for Analyzing Gene Frequencies in Natural Populations, Itogi Nauki Tekhn., Ser.: Obshch. Genet., Moscow: VINITI, 1983, vol. 8, pp. 76-104.Google Scholar
  22. 22.
    Lell, J.T., Brown, M.D., Schurr, T.G., et al., Y Chromosome Polymorphisms in Native American and Siberian Populations: Identification of Native American Y Chromosome Haplotypes, Hum. Genet., 1997, vol. 100, pp. 536-543.Google Scholar
  23. 23.
    Quintana-Murci, L., Krausz, C., Zerjal, T., et al., Y-Chromosome Lineages Trace Diffusion of People and Languages in Southwestern Asia, Am. J. Hum. Genet., 2001, vol. 68, pp. 537-542.Google Scholar
  24. 24.
    Derenko, M.V., Malyarchuk, B.A., Dambueva, I.K., et al., Mitochondrial DNA Variation in Two South Siberian Aboriginal Populations: Implications for the Genetic History of North Asia, Hum. Biol., 2000, vol. 72, pp. 945-973.Google Scholar
  25. 25.
    Derenko, M.V., Denisova, G.A., Malyarchuk, B.A., et al., Gene Pool Structure in Ethnic Groups of the Altai-Sayan Uplands, as Revealed by Mitochondrial DNA Polymorphisms, Genetika (Moscow), 2001, vol. 37, no. 10, pp. 1402-1410.Google Scholar
  26. 26.
    Viktorova, T.V., Bermisheva, M.A., and Shagina, I.V., Polymorphism of the Y-Chromosomal DYS19 and DYS393 Microsatellite Loci and Frequency of T-C Transition of Locus RGFS in Ethnoses of the Volga-Ural Region, Genetika (Moscow), 2000, vol. 36, no. 8, pp. 1150-1156.Google Scholar
  27. 27.
    Stepanov, V.A. and Puzyrev, V.P., Haplotypes of Two Diallelic Loci of the Y Chromosome in the Indigenous and Migrant Populations of Siberia, Genetika (Moscow), 2000, vol. 36, no. 1, pp. 87-92.Google Scholar
  28. 28.
    Potapov, L.P., Ocherki narodnogo byta tuvintsev (Essays on the Traditional Life of Tuvinians), Moscow: Nauka, 1969.Google Scholar

Copyright information

© MAIK “Nauka/Interperiodica” 2002

Authors and Affiliations

  • M. V. Derenko
    • 1
  • B. A. Malyarchuk
    • 1
  • G. A. Denisova
    • 1
  • Ch. M. Dorzhu
    • 2
  • O. N. Karamchakova
    • 3
  • F. A. Luzina
    • 4
  • E. A. Lotosh
    • 4
  • I. K. Dambueva
    • 5
  • U. N. Ondar
    • 2
  • I. A. Zakharov
    • 3
  1. 1.Institute of Biological Problems of the NorthRussian Academy of SciencesMagadanRussia
  2. 2.Tuva State UniversityKyzylRussia
  3. 3.Vavilov Institute of General GeneticsMoscowRussia
  4. 4.Institute of Occupational Diseases and HygieneNovokuznetskRussia
  5. 5.Institute of General and Experimental BiologyRussian Academy of SciencesUlan-UdeRussia

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