Journal of Behavioral Medicine

, Volume 25, Issue 2, pp 175–193 | Cite as

The PedsQLTM 4.0 Generic Core Scales: Sensitivity, Responsiveness, and Impact on Clinical Decision-Making

  • James W. Varni
  • Michael Seid
  • Tara Smith Knight
  • Karen Uzark
  • Ilona S. Szer


The PedsQLTM 4.0 (Pediatric Quality of Life InventoryTM) Generic Core Scales are child self-report and parent proxy-report scales developed to measure health-related quality of life (HRQOL) in children and adolescents ages 2–18. The PedsQLTM 4.0 Generic Core Scales consist of 23 items applicable for healthy school and community populations and pediatric populations with acute and chronic health conditions. The 4 PedsQLTM 4.0 Generic Core Scales (Physical, Emotional, Social, School) were administered to 209 children and 269 parents (289 subjects accrued overall) recruited from pediatric cardiology, orthopedics, and rheumatology clinics. Sensitivity, responsiveness, and the impact on clinical decision-making were determined. The PedsQLTM was differentially sensitive to increasing degrees of cardiac disease severity in the cardiology clinic setting and responsive to clinical change over time in the pediatric orthopedics clinic setting. In the pediatric rheumatology clinic setting, the PedsQLTM demonstrated an impact on clinical decision-making, resulting in subsequent increases in HRQOL.

health-related quality of life pediatrics children cardiology orthopedics rheumatology 


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Copyright information

© Plenum Publishing Corporation 2002

Authors and Affiliations

  • James W. Varni
    • 1
    • 2
  • Michael Seid
    • 1
  • Tara Smith Knight
    • 1
  • Karen Uzark
    • 3
  • Ilona S. Szer
    • 4
    • 5
  1. 1.Center for Child Health OutcomesChildren's Hospital and Health CenterSan Diego
  2. 2.Department of PsychiatryUniversity of CaliforniaSan Diego, School of Medicine
  3. 3.Children's Heart InstituteChildren's Hospital and Health CenterSan Diego
  4. 4.Division of Pediatric RheumatologyChildren's Hospital and Health CenterSan Diego
  5. 5.Department of PediatricsUniversity of CaliforniaSan Diego, School of Medicine

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