Breast Cancer Research and Treatment

, Volume 70, Issue 2, pp 137–143

Survival of women with breast cancer in France: variation with age, stage and treatment

  • Pascale Grosclaude
  • Marc Colonna
  • Guy Hedelin
  • Brigitte Tretarre
  • Patrick Arveux
  • Josette Mace Lesec'h
  • Nicole Raverdy
  • Martine Sauvage-Machelard
Article

Abstract

This study examines survival of women with breast cancer using a sample of 1564 cases occurring in 1990 taken from all cases recorded in seven French cancer registries. Age at diagnosis pathological stage (pTNM) and treatment were the criteria selected for the study of the survival. We studied the 5-year observed survival and the relative survival. Tumors pT1 represented 46.7% cases, pT2: 31.6%, pT3 and pT4: 9.2%, and 52% of the tumors had no nodal involvement or metastasis. For cases without surgical treatment the prognosis was poor (observed survival 18.7%, relative survival 25.9%). For women benefiting from neoadjuvant treatment, observed survival rate was 65% after 5 years and relative survival rate 69.1%. For women who were treated first with surgery, the observed survival was 79.5% and the relative survival 86.7%. The survival rate for women under 40 years was slightly lower than for the 40–54-year-old. Using relative survival the youngest group had the worst prognosis and the oldest group the best. In older women, therapeutic strategy might have been more selective which leads to a better prognosis than in the younger age groups treated in a comparable way.

breast cancer epidemiologic study population based registry stage at diagnosis survival 

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References

  1. 1.
    Menegoz F, Black RJ, Arveux P, Magne V, Ferlay J, Buemi A, Carli PM, Chapelain G, Faivre J, Gignoux M, Grosclaude P, Mace-Lesec'h J, Raverdy N, Schaffer P: Cancer incidence and mortality in France in 1975-1995. Eur J Cancer Prev 6: 442-466, 1997Google Scholar
  2. 2.
    Quinn MJ, Martinez-Garcia C, Berrino F, Eurocare working group: Variations in survival from breast cancer in Europe by age and country, 1978-1989. Euro J Cancer 34: 2204-2211, 1998Google Scholar
  3. 3.
    UICC: TNM Atlas. 3rd edn, 2nd revision, Springer-Verlag, Berlin, 1992Google Scholar
  4. 4.
    UICC: TNM Classification of Malignant Tumours. 5th edn, Wiley, New York, 1997Google Scholar
  5. 5.
    Kiricuta CI, Tausch J: A mathematical model of axillary lymph node involvement based on 1446 complete axillary dissections in patients with breast carcinoma. Cancer 69: 2496-2501, 1992Google Scholar
  6. 6.
    Esteve J, Benhamou E, Croasdale M, Raymond L: Relative survival and the estimation of net survival: elements for further discussion. Stat Med 9: 529-538, 1990Google Scholar
  7. 7.
    Brass W: On the scale of mortality. In: Brass W (ed) Biological Aspect of Demograph. Taylor and Francis, London, 1971, pp 69-110Google Scholar
  8. 8.
    Coleman M, Babb P, Damiecki P, Grosclaude P, Honjo S, Jones J, Knerer G, Pitard A, Quinn M, Slogett A, De Stavola B: Cancer Survival in England and Wales, 1971-1995: Deprivation and NHS Region. The Stationery Office, Londres, 1999, p 695Google Scholar
  9. 9.
    StataCorp: Stata Statistical Software Release 5.0 College Station. TX: Stata Corporation, 1997Google Scholar
  10. 10.
    Hedelin G: Relsurv a Program for Relative Survival. Technical Report of Epidemiology and Public Health, Faculty of Medicine Louis Pasteur, Strasbourg, 1995Google Scholar
  11. 11.
    Bergman L, Kluck HM, van Leeuwen FE, Crommelin MA, Dekker G, Hart AAM, Coebergh JW: The influence of age on treatment choice and survival of elderly breast cancer patients in south-eastern Netherlands: a population-based study. Eur J Cancer 28A: 1475-1480, 1992Google Scholar
  12. 12.
    Wanebo H J, Cole B, Chung M, Vezeridis M, Schepps B, Fulton J, Bland K: Is surgical management compromised in elderly patients with breast cancer? Ann Surg 225: 579-586, 1997Google Scholar
  13. 13.
    Sant M, Capocaccia R, Verdecchia A, Esteve J, Gatta G, Micheli A, Coleman MP, Berrino F: Survival of women with breast cancer in Europe: variation with age, year of diagnosis and country. The Eurocare working group. Int J Cancer 77: 679-683, 1998Google Scholar
  14. 14.
    Berrino F, Capocaccia R, Esteve J, Gatta G, Hakulinen T, Micheli A, Sant M, Verdecchia A (eds): Survival of cancer patients in Europe: the Eurocare-2 study. IARC Scientific Publication no 151, Lyon, 1999, p 572Google Scholar

Copyright information

© Kluwer Academic Publishers 2001

Authors and Affiliations

  • Pascale Grosclaude
    • 1
  • Marc Colonna
    • 2
  • Guy Hedelin
    • 3
  • Brigitte Tretarre
    • 4
  • Patrick Arveux
    • 5
  • Josette Mace Lesec'h
    • 6
  • Nicole Raverdy
    • 7
  • Martine Sauvage-Machelard
    • 1
  1. 1.Registre des Cancers du Tarn, Chemin des Trois TarnAlbiFrance
  2. 2.Registre des Cancers de l'IsèreMeylanFrance
  3. 3.Registre Bas-Rhinois des Cancers, Faculté de MedecineStrasbourgFrance
  4. 4.Registre des Cancers de l'HéraultMontpellierFrance
  5. 5.Registre des Cancers du DoubsFaculté de MédecineBesanconFrance
  6. 6.Registre des Cancers du CalvadosCentre François BaclesseCaenFrance
  7. 7.Registre des Cancers de la SommeCHU MédecineAmiensFrance

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