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Journal of Computational Neuroscience

, Volume 11, Issue 2, pp 95–110 | Cite as

Recovering Quasi-Active Properties of Dendritic Neurons from Dual Potential Recordings

  • Steven J. Cox
  • Boyce E. Griffith
Article

Abstract

We develop the theory and accompanying algorithm for the recovery of a dendritic neuron's cytoplasmic resistivity, membrane capacitance, leakage conductance, and two maximal channel conductances from weighted averages of simultaneous recordings of somatic and dendritic potential following a somatic current stimulus. We test our results on two model systems with distinct, though prescribed, channel kinetics and branching patterns.

identification parameter estimation moment methods symbolic solution Laplace transform 

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Copyright information

© Kluwer Academic Publishers 2001

Authors and Affiliations

  • Steven J. Cox
    • 1
  • Boyce E. Griffith
    • 1
  1. 1.Department of Computational and Applied MathematicsRice UniversityHouston

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