Digestive Diseases and Sciences

, Volume 46, Issue 12, pp 2681–2686 | Cite as

Cytological Screening for Barrett's Esophagus Using a Prototype Flexible Mesh Catheter

  • Anne E. Rader
  • Douglas O. Faigel
  • John Ditomasso
  • Nathan Magaret
  • Michael Burm
  • M. Brian Fennerty


The current cost of endoscopically screening patients with gastroesophageal reflux disease (GERD) and Barrett's esophagus (BE) is considerable. A nonendoscopic device that allows for screening of these patients would offer significant cost savings. This pilot study evaluates the utility of cytologically diagnosing BE using a prototype flexible mesh catheter. Patients with known BE undergoing indicated surveillance endoscopy were enrolled in the study. Cytology specimens were obtained using a prototype flexible catheter and were evaluated for the presence of glandular cells, goblet cells, squamous cells, inflammation, and dysplasia. Eleven patients with BE were enrolled in the study. None of the patients experienced complications. Specimens from eight patients (73%) were adequate for evaluation and seven of these patients (87.5%) had goblet cells diagnostic for BE. In conclusion, flexible mesh catheters potentially offer a sensitive, inexpensive, and minimally invasive approach to evaluating patients with GERD and BE.

Barrett's esophagus catheter gastroesophageal reflux disease screening 


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Copyright information

© Plenum Publishing Corporation 2001

Authors and Affiliations

  • Anne E. Rader
    • 1
  • Douglas O. Faigel
    • 2
  • John Ditomasso
    • 3
  • Nathan Magaret
    • 2
  • Michael Burm
    • 2
  • M. Brian Fennerty
    • 2
  1. 1.Department of PathologyOregon Health Sciences University and Veterans Administration Medical CenterPortland
  2. 2.Department of Medicine, Division of GastroenterologyOregon Health Sciences University and Veterans Administration Medical CenterPortland
  3. 3.Pathology Consultants, P.C.Eugene

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