, Volume 2, Issue 3, pp 155–164 | Cite as

Effects of mild heat shocks at young age on aging and longevity in Drosophila melanogaster

  • Éric Le Bourg
  • Philippe Valenti
  • Patrice Lucchetta
  • François Payre


Young adult flies were submitted to heat shocks (37°C) ofvarious durations (5, 10, 20, 40 or 60 min daily) for 1, 2 or 3 weeks. Aslight longevity increase, in both sexes, was only observed with thelowest heat shock. Longer shocks had neutral or negative effects. Fliessubmitted to the procedure providing a longevity increase did not show adelayed behavioral aging but survived longer at 37°C thancontrol flies. This higher thermotolerance was not associated with anincreased hsp70 induction. The results are discussed in connection withhormesis and previous results showing that hypergravity, an other mildstress, increases longevity and delays behavioral aging: different mildstresses may have contrasting effects on aging and longevity.

aging heat-shock heat-shock proteins longevity locomotor activity thermotolerance Drosophila melanogaster hormesis 


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Copyright information

© Kluwer Academic Publishers 2001

Authors and Affiliations

  • Éric Le Bourg
    • 1
  • Philippe Valenti
    • 2
  • Patrice Lucchetta
    • 1
  • François Payre
    • 2
  1. 1.Laboratoire d'Éthologie et de Cognition Animale, F.R.E. C.N.R.S. no. 2382Université Paul-SabatierToulouse cedex 4France (e-mail:
  2. 2.Centre de Biologie du Développement, U.M.R. C.N.R.S. no. 5547Université Paul-SabatierToulouse cedex 4France

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