Objective: A high level of completeness of case-finding is essential if data from cancer registries are to be useful for comparative studies. A large case series, collected independently of the cancer registry case-finding mechanisms, as part of a study of the influence of HIV infection on cancer risk, was used to evaluate the completeness of the registry in Kampala, Uganda, for the years 1994–1996.
Results: For adults aged 15 or more, the completeness of registration of diagnosed cancer cases was 89.6% (95% CI 87.0–91.7) overall. It varied with age (better ascertainment of younger cases, aged under 30) and cancer site (with Kaposi sarcoma cases significantly better identified), and cases with a histology report were more likely to be registered than those without (though the difference was not significant). Completeness declined with time, as in most registries, which continue to identify “late” cases some time after the initial diagnosis.
Conclusion: This is the first objective measurement of completeness of cancer registration in Africa, and it gives reassurance that published incidence rates are reasonably accurate (provided that there is not an insistence on the very latest results).
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- 1.Jensen OM, Storm HH (1991) Reporting of results. In: Jensen OM, Parkin DM, MacLennan R, Muir CS, Skeet R, eds. Cancer Registration: Principles and Methods. IARC Scientific Publication No. 95, Lyon: IARC, pp. 108-125.Google Scholar
- 2.Parkin DM, Chen VW, Ferlay J, Galceran J, Storm HH, Whelan SL (1994) Comparability and Quality Control in Cancer Registration. IARC Technical Report No. 19. Lyon: IARC.Google Scholar
- 3.Wabinga HR, Parkin DM, Wabwire-Mangen F, Nambooze S (2000) Trends in cancer incidence in Kyadondo County, Uganda, 1960-1997. Br J Cancer 82: 1585-1592.Google Scholar
- 4.Percy C, Van Holten V, Muir C, eds. (1990) International Classification of Diseases for Oncology, 2nd edn. Geneva: WHO.Google Scholar
- 5.Cooke A (1998) Canreg3 Manual. In: Internal Report No. 98/03. Lyon: IARC.Google Scholar
- 6.Ziegler JL, Newton R, Katongole-Mbidde E, et al., for the Uganda Kaposi Sarcoma Study Group (1997) Risk factors for Kaposi's sarcoma in HIV positive subjects in Uganda. AIDS 11: 1619-1626.Google Scholar
- 7.Newton R, Ziegler J, Beral V, et al., and the Uganda Kaposi's Sarcoma Study Group (1999) HIV and cancer in adults and children in Kampala, Uganda. J Acquir Immune Defic Syndr Human Retrovirol 21: A10.Google Scholar
- 8.StataCorp (1997) Stata Statistical Software: Release 5.0. College Station, TX: Stata Corporation.Google Scholar
- 9.Storm HH (1988) Completeness of cancer registration in Denmark 1943-1966 and efficacy of record linkage procedures. Int J Epidemiol 17: 44-49.Google Scholar
- 10.Swerdlow AJ, Douglas AJ, Vaughan Hudson G, Vaughan Hudson B (1993) Completeness of cancer registration in England and Wales: an assessment based on 2,145 patients with Hodgkin' s disease independently registered by the British National Lymphoma Investigation. Br J Cancer 67: 326-329.Google Scholar
- 11.Nwene U, Smith A (1982) Assessing completeness of cancer registration in the north-western region of England by a method of independent comparison. Br J Cancer 46: 635-639.Google Scholar
- 12.Villard-Mackintosh L, Coleman MP, Vessey MP (1988) The completeness of cancer registration in England: an assessment from the Oxford-FPA contraceptive study. Br J Cancer 58: 507-511.Google Scholar
- 13.Schouten LJ, Hoppener P, van den Brandt PA, Knottnerus JA, Jager JJ (1993) Completeness of cancer registration in Limburg, The Netherlands. Int J Epidemiol 22: 369-376.Google Scholar
- 14.Skeet RG (1991) Quality and quality control. In: Jensen OM, Parkin DM, MacLennan R, Muir CS, Skeet R, eds. Cancer Registration: Principles and Methods. IARC Scientific Publications No. 95. Lyon: IARC.Google Scholar