Biomechanical and biological properties of the implant material carbon-carbon composite covered with pyrolytic carbon

  • V. PesÁkovÁ
  • Z. Kle´zl
  • K. Bali´k
  • M. Adam


The aim of this study was to test C/C material (carbonized, graphitized or covered with pyrolytic carbon) designated for the use in orthopaedic and bone surgery. Using an in vitro assay we confirmed, that the cell proliferation was exhibited the mostly on the C/C composite coated with pyrolitic carbon and afterwards polished. The two latest of subsequent water extracts of this material had a slightly inhibiting effect on the cells metabolic activity. Biocompatibility test in vivo performed subcutaneously on rats did not show big differences between three tested implants (C/C composite, epoxy resine, titanium alloy), on the other hand the plates tested on pigs demonstrated foreign-body reaction induced by wear C/C composite material. Such debris were found both in the neighborhood of the implant as well as in the lymphatic node.


Titanium Epoxy Titanium Alloy Biological Property Water Extract 
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Copyright information

© Kluwer Academic Publishers 2000

Authors and Affiliations

  • V. PesÁkovÁ
    • 1
  • Z. Kle´zl
    • 2
  • K. Bali´k
    • 3
  • M. Adam
    • 1
  1. 1.Rheumatism InstitutePrague 2Czech Republic
  2. 2.Orthopaedic-Traumatology DepartmentCentral Military HospitalPrague 6Czech Republic
  3. 3.Institute of Rock Structure and Mechanics, Acad. Sci. CRPrague 8Czech Republic

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