Quality of Life Research

, Volume 9, Issue 2, pp 177–184

The EORTC breast cancer-specific quality of life questionnaire (EORTC QLQ-BR23): Translation and validation study of the Iranian version

  • A. Montazeri
  • I. Harirchi
  • M. Vahdani
  • F. Khaleghi
  • S. Jarvandi
  • M. Ebrahimi
  • M. Haji-Mahmoodi
Article

Abstract

The objective of this study was to test the reliability and validity of the Iranian version of the European Organization for Research and Treatment of Cancer (EORTC) Breast Cancer-Specific Quality of Life Questionnaire (QLQ-BR23). The English-language version of the questionnaire was translated into Persian (Iranian language) and its final form was approved by the EORTC Study Group on Quality of Life and then it was used in this study. The questionnaire was administered at two points in time to a consecutive sample of 168 newly diagnosed breast cancer patients and almost all of them (99%) found the questions easy to understand and acceptable. Cronbach's α coefficient for multi-item scales (to test reliability) ranged from 0.63 to 0.95 at baseline and from 0.75 to 0.92 at follow-up administration of the questionnaire. Validity analysis was performed using known-groups' comparison analysis. The results showed that all functional and symptom scales discriminated between sub-groups of patients differing in clinical status as defined by their performance status and disease stage. In addition, all functional and symptoms scales detected change over time, as a function of changes in patients' performance status. In general, the findings of this study indicated that the Iranian version of the EORTC QLQ-BR23 is a reliable and valid supplementary measure of the quality of life in breast cancer patients and can be used in clinical trials and studies of outcome research in oncology.

Breast cancer EORTC QLQ-BR23 Iran Quality of life Validation study 

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References

  1. 1.
    Gill TM, Feinstein AR. A critical appraisal of the quality of life measurements. JAMA 1994; 272: 619-626.Google Scholar
  2. 2.
    Fallowfield L. Quality of quality of life data. Lancet 1996; 348: 421.Google Scholar
  3. 3.
    Sanders C, Egger M, Donovan J, Tallon D, Frankel S. Reporting on quality of life in randomized controlled trials: bibliographic study. Br Med J 1998; 317: 1191-1194.Google Scholar
  4. 4.
    Winer EP. Quality of life research in patients with breast cancer. Cancer 1994; 74: 410-415.Google Scholar
  5. 5.
    Bowling A. Measuring disease: a review of disease-specific quality of life measurement scales. Buckingham: Open University Press, 1995.Google Scholar
  6. 6.
    Montazeri A, Harirchi I, Vahdani M, et al. The Euro-pean Organization for research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30): translation and validation study of the Iranian version. Support Care Cancer 1999; 7: 400-406.Google Scholar
  7. 7.
    Sprangers MAG, Groenvold M, Arraras JI, et al. The European Organization for Research and Treatment of Cancer Breast Cancer-Specific Quality of Life Question-naire module: first results from a three-country field study. J Clin Oncol 1996; 14: 2756-2768.Google Scholar
  8. 8.
    Cull A, Sprangers M, Aaronson N. EORTC quality of life study group translation procedure (Internal report). Brussels: EORTC Quality of Life Study Group, 1994.Google Scholar
  9. 9.
    Zubord CG, Scheiderman MA, Frei E. Appraisal of methods for the study of chemotherapy in man: compara-tive therapeutic trial of nitrogen mustard and triethylene thiopphosphoramide. J Chro Dis 1960; 11: 7-33.Google Scholar
  10. 10.
    Cronbach LJ. Coefficient alpha and the internal structure of tests. Psychometrika 1951; 16: 297-334.Google Scholar
  11. 11.
    Nunnally JC. Psychometric theory. New York: McGraw-Hill, 1994.Google Scholar
  12. 12.
    Kerlinger FN. Foundations of behavioral research. New York: Holt, Rinehart & Winston, 1973.Google Scholar
  13. 13.
    Fayers P, Aaronson N, Bjordal, Sullivan M. EORTC-C30 scoring manual. Brussels: EORTC Study Group on Quality of Life, 1995.Google Scholar
  14. 14.
    Hunt SM. Cross-cultural issues in the use of sociomedical indicators. Health Policy 1986; 6: 149-158.Google Scholar
  15. 15.
    Hunt SM, Alonso J, Bucquet D, Niero M, Wiklund I, McKenna S. Cross cultural adaptation of health measures. Health Policy 1991; 19: 33-44.Google Scholar
  16. 16.
    Brady MJ, Cella DF, Mo F, et al. Reliability and validity of the Functional Assessment of Cancer Therapy Breast quality oflife instrument. J Clin Oncol 1997; 15: 974-986.Google Scholar
  17. 17.
    Cella D, Hernandez L, Bonomi AE, et al. Spanish language translation and initial validation of the functional assess-ment of cancer therapy quality of life. Med Care 1998; 36: 1407-1418.Google Scholar
  18. 18.
    Hann DM, Jacobsen PB, Azzarello LM, et al. Measure-ment of fatigue in cancer patients: development and validation of the Fatigue Symptom Inventory. Qual Life Res 1998; 7: 301-310.Google Scholar
  19. 19.
    Bjordal K, Hammerlid E, Ahlner-Elmqvist M, et al. Quality of life in head and neck cancer patients: validation of the European Organization for Research and Cancer Treatment Quality of Life Questionnaire-H&N35. J Clin Oncol 1999; 17: 1008-1019.Google Scholar
  20. 20.
    Kobayashi K, Takeda F, Teramukai S, et al. A cross-vali-dation of the European Organization for Research and Treatment of Cancer QLQ-C30 (EORTC QLQ-C30) for Japanese with lung cancer. Eur J Cancer 1998; 34: 810-815.Google Scholar
  21. 21.
    Aaronson NK, Ahmedzai S, Bergman B, et al. The Euro-pean Organization for Research and Treatment of Cancer QLQ-C30: a quality of life instrument for use in interna-tional clinical trials in oncology. J Natl Cancer Inst 1993; 85: 365-376.Google Scholar
  22. 22.
    Sprangers MAG, Cull A, Bjordal K, Groenvold M, Aaronson NK. The European Organization for Research and Treatment of Cancer approach to quality of life assessment: guideline for developing questionnaire modules. Qual Life Res 1993; 2: 287-295.Google Scholar
  23. 23.
    Sprangers MAG, Cull A, Groenvold M, Bjordal K, Blazeby J, Aaronson NK. The European Organization for Research and Treatment of Cancer approach to developing questionnaire modules: an update and overview. Qual Life Res 1998; 7: 291-300.Google Scholar

Copyright information

© Kluwer Academic Publishers 2000

Authors and Affiliations

  • A. Montazeri
    • 1
  • I. Harirchi
    • 2
  • M. Vahdani
    • 3
  • F. Khaleghi
    • 4
  • S. Jarvandi
    • 4
  • M. Ebrahimi
    • 4
  • M. Haji-Mahmoodi
    • 4
  1. 1.Iranian Centre for Breast Cancer (ICBC)TehranIran
  2. 2.Iranian Centre for Breast Cancer (ICBC)TehranIran
  3. 3.Iranian Centre for Breast Cancer (ICBC)TehranIran
  4. 4.Iranian Centre for Breast Cancer (ICBC)TehranIran

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