Compliance with prescribed drugs: challenges for the elderly population Article DOI:
10.1023/A:1008786004974 Cite this article as: Claesson, S., Morrison, A., Wertheimer, A. et al. Pharm World Sci (1999) 21: 256. doi:10.1023/A:1008786004974 Abstract
Compliance with prescribed drug regimens is particularly important among the elderly because of their increased vulnerability and greater burden of chronic disorders. This narrative review discusses the factors that are important to compliance, with particular reference to the elderly. These factors are the patient's perceptions of his disease and it's treatment, the physician's perceptions, the manner the physician assumes and the language he uses to communicate with the patient, the patient's living situation, regular medication review, and a continuity of health care provision. Since it is the patient who decides how to use the therapy, his or her involvement in the process of explaining and understanding it is the key to improved compliance.
Aged Counseling Drug Therapy Patient Compliance Prescriptions, Drug References
Baum C, Kennedy DL, Forbes MB, Jones JK. Drug use in the United States in 1981.
Pegels CC. Health care expenditures for the elderly: a current and future dilemma.
Socioecon Plann Sci.
Hussar DA. Patient compliance. In: Gennaro AR, Editor.
Remington: The Science and Practice of Pharmacy.19th ed. Mack Publishing Company; 1995:1796-1807.
Stewart RB, Caranasos GJ. Medication compliance in the elderly.
Med Clin North Am.
McCaul KD, Glasgow RE, Schafer LC. Diabetes regimen behaviors. Predicting adherence.
Salzman C. Medication compliance in the elderly.
J Clin Psychiatry
. 1995;56Suppl 1:18-22; discussion 23.
Monane M, Bohn RL, Gurwitz JH, Glynn RJ, Avorn J. Noncompliance with congestive heart failure therapy in the elderly.
Arch Intern Med.
Boyd JR, Covington TR, Stanaszek WF, Coussons RT. Drug defaulting. I. Determinants of compliance.
Am J Hosp Pharm.
Haynes RB. A critical review of the “determinants” of patient compliance with therapeutic regimens. In: Sackett DL, Haynes RB, Editors.
Compliance With Therapeutic Regimens
. Baltimore: John Hopkins University Press; 1976:26-39.
Strogatz DS, Earp JA. The determinants of dropping out of care among hypertensive patients receiving a behavioral intervention.
Jay S, Litt IF, Durant RH. Compliance with therapeutic regimens.
J Adolesc Health Care
Edwards M, Pathy MS. Drug counselling in the elderly and predicting compliance.
Sharkness CM, Snow DA. The patient's view of hypertension and compliance.
Am J Prev Med.
Balkrishnan R. Predictors of medication adherence in the elderly.
Curtin RB, Svarstad BL, Andress D, Keller T, Sacksteder P. Differences in older versus younger hemodialysis patients' noncompliance with oral medications.
Geriatr Nephrol Urol.
Pratt JH, Jones JJ. Noncompliance with therapy; an on-going problem in treating hypertension.
Noncompliance with medication regimens: detection and intervention.
National Pharmaceutical Council. 1992;2:1-20.
Kovar MG. Morbidity and health care utilization. In: Haynes SG, Feinlab M, Editors.
Epidemiology of Aging
. Bethesda, MA.: National Institutes of Health. 1980:317-22.
Snader TC. Long-term care facilities. In: Gennaro AR, Editor.
Remington: The Science and Practice of Pharmacy.19th ed. Mack Publishing Company; 1995:1740-54.
Adelman RC. Definition of biological aging. In: Haynes SG, Feinlab M, Editors.
Epidemiology of Aging
. Bethesda, MA.: National Institutes of Health. 1980:12.
Weksler ME. Genetic and immunological determinants of aging. In: Haynes SG, Feinlab M, Editors.
Epidemiology of Aging
. Bethesda, MA.: National Institutes of Health. 1980:18.
Monane M, Monane S, Semla T. Optimal medication use in elders. Key to successful aging.
West J Med.
Blenkiron P. The elderly and their medication: understanding and compliance in a family practice.
Postgrad Med J.
Cramer JA. Enhancing patient compliance in the elderly. Role of packaging aids and monitoring.
Kruse W, Koch-Gwinner P, Nikolaus T, Oster P, Schlierf G, Weber E. Measurement of drug compliance by continuous electronic monitoring: a pilot study in elderly patients discharged from hospital.
J Am Geriatr Soc.
Pullar T, Birtwell AJ, Wiles PG, Hay A, Feely MP. Use of a pharmacologic indicator to compare compliance with tablets prescribed to be taken once, twice, or three times daily.
Clin Pharmacol Ther.
Farmer KC, Jacobs EW, Phillips CR. Long-term patient compliance with prescribed regimens of calcium channel blockers.
1994;16:316-26; discussion 271-2.
Fitten LJ, Coleman L, Siembieda DW, Yu M, Ganzell S. Assessment of capacity to comply with medication regimens in older patients.
J Am Geriatr Soc.
McElnay JC, Thompson J. Dispensing of medicines in compliance packs.
Int Pharm J.
Nagy VT, Wolfe GR. Cognitive predictors of compliance in chronic disease patients.
Fincham JE, Wertheimer AI. Using the health belief model to predict initial drug therapy defaulting.
Soc Sci Med.
Dowell J, Hudson H. A qualitative study of medication-taking behaviour in primary care.
Sclar DA, Chin A, Skaer TL, Okamoto MP, Nakashiro RK, Gill MA. Effect of health education on the utilization of antihypertensive therapy: a prospective trial among HMO enrollees.
Gilbert JR, Evans CE, Haynes RB, Tugwell P. Predicting compliance with a regimen of digoxin therapy in family practice.
Can Med Assoc J.
Inui TS, Yourtee EL, Williamson JW. Improved outcomes in hypertension after physician tutorials. A controlled trial.
Ann Intern Med.
Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence.
Manson A. Language concordance as a determinant of patient compliance and emergency room use in patients with asthma.
Steele DJ, Jackson TC, Gutmann MC. Have you been taking your pills? The adherence-monitoring sequence in the medical interview.
J Fam Pract.
McKenney JM, Munroe WP, Wright JT Jr. Impact of an electronic medication compliance aid on long-term blood pressure control.
J Clin Pharmacol.
Straka RJ, Fish JT, Benson SR, Suh JT. Patient self-reporting of compliance does not correspond with electronic monitoring: an evaluation using isosorbide dinitrate as a model drug.
Urquhart J. Patient non-compliance with drug regimens: measurement, clinical correlates, economic impact
. Eur Heart J.
Google Scholar Copyright information
© Kluwer Academic Publishers 1999