Pharmacy World and Science

, Volume 19, Issue 2, pp 89–92 | Cite as

The anaesthetist as determinant factor of quality of surgical antimicrobial prophylaxis. A survey in a university hospital.

  • I.C. Gyssens
  • J.T.A. Knape
  • G. Van Hal
  • J.W.M. van der Meer


In actual surgical antimicrobial prophylaxis, the anaesthetist administers the drugs at induction of anaesthesia. In the first phase of our quality‐of‐use intervention study on antimicrobial drugs in a large university hospital, information on the practice of antimicrobial prophylaxis was needed. The staff of 44 anaesthetists was interviewed by means of a questionnaire. Response rate was 36/44 (82%). The anaesthetists' method of administering surgical prophylaxis was rather uniform and inexpensive: cephalosporins were almost exclusively administered by bolus method. The main reason was that infusion was more cumbersome (range 77‐85%). Communication between surgeon and anaesthetist was reported to be poor, and in two out of three operating departments, orders of prophylaxis transmitted at or after induction accounted for more than 80%. Seventy‐seven percent of the responders asked the surgeon if prophylaxis was necessary if they were in doubt; 20% responded that they checked it systematically. The data collected by the inquiry proved useful in the process of optimizing surgical prophylaxis in our hospital.

Anaesthesiology Antibiotics Cost Hospital Pharmacy Surgical prophylaxis 


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Copyright information

© Kluwer Academic Publishers 1997

Authors and Affiliations

  • I.C. Gyssens
    • 1
    • 2
  • J.T.A. Knape
    • 3
  • G. Van Hal
    • 4
  • J.W.M. van der Meer
    • 1
  1. 1.Dept. of General Internal MedicineUniversity HospitalNijmegen
  2. 2.Dept of Clinical MicrobiologyUniversity Hospital RotterdamRotterdamThe Netherlands
  3. 3.Department of AnaesthesiologyUniversity Hospital Nijmegen,presently: Institute of Anaesthesiology, University HospitalUtrechtThe Netherlands
  4. 4.Department of EpidemiologyUniversity of AntwerpBelgium

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