Journal of Applied Phycology

, Volume 12, Issue 3–5, pp 543–547 | Cite as

Bioactivity in free-living and symbiotic cyanobacteria of the genus Nostoc

  • Raffaella Piccardi
  • Andrea Frosini
  • Mario R. Tredici
  • Maria C. Margheri


Fifty cyanobacterial strains from different habitats(symbioses, soil, fresh and marine waters) belongingto the genus Nostoc were cultured and tested forbioactivity. Thirty-seven strains were isolated in ourlaboratory, the remaining were supplied by officialculture collections. All the organisms were grownunder controlled laboratory conditions. The biomasseswere lyophilised and extracted with ethanol:water toobtain a hydrophilic extract and then withdichloromethane:isopropanol to obtain a lipophilicextract. Both crude extracts were tested forantifungal (against Penicillium expansum andRhizoctonia solani) and antibacterial activity(against Agrobacterium vitis, Escherichiacoli and Staphylococcus epidermidis), and fortoxicity against Artemia salina nauplii.Twenty-four strains showed activity against at leastone of the target organisms. Bioactivity was equallydistributed between lipophilic and hydrophilicextracts, and was mostly directed against fungi (15strains) and Artemia nauplii (12 strains);antibacterial activity was less frequent (8 strains).The presence of bioactivity was independent of thestrain origin.

antifungal and antibacterial compounds bioactivity cyanobacteria cytotoxicity Nostoc 


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Copyright information

© Kluwer Academic Publishers 2000

Authors and Affiliations

  • Raffaella Piccardi
    • 1
  • Andrea Frosini
    • 1
  • Mario R. Tredici
    • 1
  • Maria C. Margheri
    • 1
  1. 1.Dipartimento di Biotecnologie AgrarieUniversità di Firenze and Centro di Studio dei Microrganismi Autotrofi, CNRFirenzeItaly

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