European Journal of Epidemiology

, Volume 15, Issue 2, pp 175–180

Outbreaks of gastroenteritis caused by SRSVs from 1987 to 1992 in Kyushu, Japan: Four outbreaks associated with oyster consumption

  • Ryuichi Otsu

DOI: 10.1023/A:1007543924543

Cite this article as:
Otsu, R. Eur J Epidemiol (1999) 15: 175. doi:10.1023/A:1007543924543


From 1987 to 1992, 18 outbreaks of acute non-bacterial gastroenteritis occurred in Kyushu district. The most common symptoms were diarrhea, vomiting, nausea and abdominal cramp. Small round structured viruses (SRSVs) were detected in 52 (44.8%) of 116 stool samples from 17 outbreaks by the electron microscopy (EM) method, and a significant increase in the antibody level was noted in 42 (80.7%) of 52 paired serum samples from 12 outbreaks by the immune electron microscopy (IEM) method and in 18 (51.4%) of 35 samples from 8 outbreaks by the western blot (WB) method. However, according to the WB method, antigen-antibody reaction was not observed to reference antigen strips (SRSV-9/Tokyo 86-510, 63kDa) in three of the 8 outbreaks. The detected virus was regarded as an etiologic agent for these outbreaks. In four of 5 outbreaks which appeared associated with eating raw oysters, there was a close relation between SRSV infection and consumption of raw oysters.

Electron microscopy Epidemiology Non-bacterial Gastroenteritis Oyster Small round structured viruses (SRSVs) 

Copyright information

© Kluwer Academic Publishers 1999

Authors and Affiliations

  • Ryuichi Otsu
    • 1
  1. 1.Fukuoka Institute of Health and Environmental Sciences, MukaizanoDazaifu, FukuokaJapan

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