European Journal of Epidemiology

, Volume 14, Issue 2, pp 153–157

Physical activity and bone mineral density in Italian middle-aged women

  • Ettore Bidoli
  • Domenico Schinella
  • Silvia Franceschi
Article

Abstract

Osteoporosis is a major health issue in postmenopausal women on account of the association between low bone mineral density and fractures. A role of physical activity in the prevention and treatment of low bone mineral density is possible but still unclear. The relationship between low spine bone mineral density measured by means of dual photon absorptiometry at lumbar spines, and levels of past and recent physical activity has been assessed by means of a population-based screening study carried out on 1373 women (age 40–64 years) in the North-East of Italy. Physical activity at work and in leisure time was investigated for three specific periods of life: at age 12, between 15 and 19 years (during bone formative years), and in the recent years prior to the interview (30–39 or 50–59 years). Data were analysed comparing low versus high bone mineral density tertile (i.e., 458 and 461 women, respectively), after controlling for other known contributory factors in the development of osteoporosis. A positive association emerged with leisure time physical activity, with significant trends at age 15–19 (odds ratio (OR) for low versus high tertile of leisure time activity: 1.4, 95% confidence interval (CI): 0.8–2.4) and at most recent age (OR: 1.7, 95% CI: 1.1–2.6). Risk trends with occupational physical activity were less clear and non-statistically significant. The present Southern European cross-sectional study lends further support to the possibility that past and recent physical activity helps increasing bone mineral density in middle-aged women. Although the most beneficial type and intensity level of exercise has yet to be determined, the present results provide further evidence that participation in even moderate exercise programs should be encouraged.

Bone mineral density Physical activity 

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References

  1. 1.
    WHO Study Group on Assessment of Fracture Risk and its Application to Screening for Postmenopausal Osteoporosis. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: Report of a World Health Organization Study Group. World Health Organ Tech Rep Ser: 843. Geneva: WHO, 1994.Google Scholar
  2. 2.
    Lyles KW, Gold DT, Shipp KM, Pieper CF, Martinez S, Mulhausen PL. Association of osteoporotic vertebral compression fractures with impaired functional status. Am J Med 1993; 94: 595–601.Google Scholar
  3. 3.
    Franceschi S, Schinella D, Bidoli E, et al. The influence of body size, smoking, and diet on bone density in preand post-menopausal women. Epidemiology 1996; 7: 411–414.Google Scholar
  4. 4.
    Cauley JA, Gutai JP, Black Sandler R, LaPorte RE, Kuller LH, Sashin D. The relationship of endogenous estrogen to bone density and bone area in normal postmenopausal women. Am J Epidemiol 1986; 124: 752–761.Google Scholar
  5. 5.
    Edelstein SL, Barrett-Connor E. Relation between body size and bone mineral density in elderly men and women. Am J Epidemiol 1993; 138: 160–169.Google Scholar
  6. 6.
    Väänänen HK. Pathogenesis of osteoporosis. Calcif Tissue Int 1991; 49 (Suppl): S11–S14.Google Scholar
  7. 7.
    Jaglal SB, Kreiger N, Darlington G. Past and recent physical activity and risk of hip fracture. Am J Epidemiol 1993; 138: 107–118.Google Scholar
  8. 8.
    Chestnut CH III. Bone mass and exercise. Consensus Development Conference on Osteoporosis. Am J Med 1993; 95 (Suppl. 5A): 34S–36S.Google Scholar
  9. 9.
    Kriska AM, Black Sandler R, Cauley JA, LaPorte RE, Hom DL, Pambianco G. The assessment of historical physical activity and its relation to adult bone parameters. Am J Epidemiol 1988; 127: 1053–1063.Google Scholar
  10. 10.
    Recker RR, Davies M, Hinders SM, Heaney RP, Stegman MR, Kimmel DB. Bone gain in young adult women. JAMA 1992; 268: 2403–2408.Google Scholar
  11. 11.
    Salvini S, Gnagnarella P, Parpinel MT, Boyle P, Decarli A, Ferraroni M, Giacosa A, La Vecchia C, Negri E, Franceschi S. The food composition database for an Italian food frequency questionnaire. J Food Comp Anal 1996; 9: 57–71.Google Scholar
  12. 12.
    FAO/OMS. Energy and protein requirements. FAO Nutr. Mtg. Rep. Ser. No. 52. Roma: FAO, 1973.Google Scholar
  13. 13.
    Breslow NE, Day NE. Statistical methods in cancer research. Vol. I. The analysis of case-control studies. IARC Sci. Publ. n. 32. Lyon: International Agency for Research on Cancer, 1980.Google Scholar
  14. 14.
    Krall EA, Dawson-Hughes B. Walking is related to bone density and rates of bone loss. Am J Med 1994; 96: 20–26.Google Scholar
  15. 15.
    Wasnich RD, Ross PD, Davis JW, Vogel JM. A comparison of single and multi-site BMC measurements for assessment of spine fracture probability. J Nucl Med 1989; 30: 1166–1171.Google Scholar
  16. 16.
    Ross PD, Wasnich RD, Vogel JM. Precision error in dual-photon absorptiometry related to source age. Radiology 1988; 166: 523–527.Google Scholar
  17. 17.
    Parazzini F, Bidoli E, Franceschi S, et al. Menopause, menstrual and reproductive history and bone density in Northern Italy. J Epidemiol Community Health 1996; 50: 519–523.Google Scholar
  18. 18.
    Greendale GA, Barrett-Connor E, Eldestein S, Ingles S, Haile R. Lifetime leisure exercise and osteoporosis. The Rancho Bernardo Study. Am J Epidemiol 1995; 141: 951–959.Google Scholar

Copyright information

© Kluwer Academic Publishers 1998

Authors and Affiliations

  • Ettore Bidoli
    • 1
  • Domenico Schinella
    • 2
  • Silvia Franceschi
    • 1
  1. 1.Servizio di Epidemiologia, Centro di Riferimento OncologicoAviano (PN)
  2. 2.Divisione di Emodialisi e NefrologiaAzienda Ospedaliera ‘S. Maria degli Angeli’PordenoneItaly

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