Mycopathologia

, Volume 147, Issue 1, pp 29–32 | Cite as

Onychomycosis in Malaysia

  • K.P. Ng
  • T.L. Saw
  • M. Madasamy
  • T.S. Soo Hoo
Article

Abstract

The common etiological agents of onychomycosis are dermatophytes, molds and yeasts. A mycological nail investigation of onychomycosis using direct microscopy and culture was conducted by the Mycology Unit, Department of Medical Microbiology, University of Malaya from March 1996 to November 1998. The study involved 878 nail clippings or subungal scrapings from subjects with onychomycosis. On direct microcopy examination, 50% of the specimens were negative for fungal elements. On culture, 373 specimens had no growth; bacteria were isolated from 15 nail specimens. Among the 490 specimens with positive fungal cultures, 177 (36.1%) were dermatophytes, 173 (35.5%) were molds and 130 (26.5%) were Candida. There were 2% (10/490) mixed infections of molds, yeasts and dermatophytes. Trichophyton rubrum (115/177) and Trichophyton mentagrophytes (59/177) were the main dermatophytes isolated. The molds isolated were predominantly Aspergillus niger (61/173), Aspergillus nidulans (30/173), Hendersonula toruloidea (26/173) and Fusarium species (16/173). 96.9% of the Candida species identified were Candida albicans.

Onychomycosis dermatophytes molds yeasts 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Zaias N. Onychomycosis. Arch Derm 1972; 105: 263–274.Google Scholar
  2. 2.
    Basnerjee U, Sethi M, Pasricha JS. Study of onychomycosis in India. Mycoses 1990; 33(7-8): 411–415.Google Scholar
  3. 3.
    Ramani R, Srinivas CR, Ramani A, Kumari TG, Shivananda PG. Molds in onychomycosis. Int J Dermatol 1993; 32(12): 877–878.Google Scholar
  4. 4.
    Lim J T-E, Hock CC, Chee LG. Dermatophytes and nondermatophyte onychomycosis in Singapore. Australas J Dermatol 1992; 33(3): 159–163Google Scholar
  5. 5.
    Clayton YM. Clinical and mycological diagnostic aspects of onychomycosis and dermatomycoses. Clin Expt Dermatol 1992; 17(suppl): 37–40.Google Scholar
  6. 6.
    Baran R, Tosti A, Piraccini BM. Uncommon clinical patterns of Fusarium nail infection: report of three cases. Br J Dermatol 1997; 136: 424–427.Google Scholar
  7. 7.
    Tosti A, Piraccini BM, Stinchi C, Lorenzi S. Onychomycosis due to Scopulariosis brevicaulis: clinical features and response to systemic antifungals. Br J Dermatol 1996; 135(5): 799–802.Google Scholar
  8. 8.
    Baran R. Proximal subungual candida onychomycosis. An unusual manifestation of chronic mucocutaneous candidosis. Br J Dermatol 1997; 137: 286–288.Google Scholar
  9. 9.
    English MP. Nails and fungi. Br J Dermatol 1976; 94: 697–701.Google Scholar
  10. 10.
    Gupta AK, Horgan-Bell CB, Summerbell RC. Onychomycosis associated with Onychocola canadensis: ten case reports and a review of the literature. J Am Acad Dermatol 1998; 39(3): 410–417.Google Scholar
  11. 11.
    Kotrajaras R, Chongsathien S, Rojanavanich V, Buddhavadhikrai P, Viriyayudhakom S. Hendersonula toruloidea infection in Thailand. Int J Dermatol 1988; 27: 391–395.Google Scholar
  12. 12.
    Walshe MM, English MP. Fungi in nails. Br J Dermatol 1966;78: 198–207. McAleer R. Fungal infections in the nails in Western Australia. Mycopathologica 1981; 73: 115-120.Google Scholar
  13. 13.
    Sigler L, Carmichael JW. Taxonomy of Malbranchea and some other hyphomycetes with arthroconidia. Mycotaxon 1976; 4(2): 349–488.Google Scholar
  14. 14.
    Campbell MC, Stewart JL. The Medical Mycology Handbook. New York: John Wiley & Sons, 1980.Google Scholar
  15. 15.
    Gentles JC. Laboratory investigations of dermatophyte infections of nails. Sabouraudia 1971; 9: 149–152.Google Scholar
  16. 16.
    English MP, Atkinson R. An improved method for the isolation of fungi in onychomycosis. Br J Dermatol 1973; 88: 237–241.Google Scholar
  17. 17.
    Blecher P, Korting HC. A new combined diagnostic approach to clinically and microscopically suspected onychomycosis unproven by culture. Mycoses 1993; 36(9-10): 321–324.Google Scholar
  18. 18.
    Elewski BE. Diagnostic techniques for confirming onychomycosis. J Am Acad Dermatol 1966; 35(3): S6–9.Google Scholar
  19. 19.
    Tosti A, Piraccini BM, Stinchi C, Lorenzi S. Onychomycosis due to Scopulariopsis brevicaulis: clinical and response to systemic antifungals. Br J Dermatol 1996; 135(5): 799–802.Google Scholar

Copyright information

© Kluwer Academic Publishers 1999

Authors and Affiliations

  • K.P. Ng
    • 1
  • T.L. Saw
    • 1
  • M. Madasamy
    • 1
  • T.S. Soo Hoo
    • 1
  1. 1.Department of Medical Microbiology, Faculty of MedicineUniversity of MalayaKuala LumpurMalaysia

Personalised recommendations