Prebiotic Formation of ADP and ATP from AMP, Calcium Phosphates and Cyanate in Aqueous Solution
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Adenosine-5′-triphosphate was synthesized by the phosphorylation of adenosine-5′-diphosphate in aqueous solution containing cyanate as a condensing reagent and insoluble calcium phosphate produced from phosphate and calcium chloride. In a similar manner, adenosine-5′-diphosphate was synthesized from adenosine-5′-monophosphate. When the experiment was carried out in the conditions of 4 °C and pH 5.75, the formation of adenosine-5′-diphosphate and adenosine-5′-triphosphate from adenosine-5′-monophosphate was observed in the yields of 19 and 7%, respectively. The other nucleoside-5′-triphosphates were also produced from their respective diphosphates.
KeywordsCalcium Phosphate Chloride Aqueous Solution Organic Chemistry
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