Prebiotic Synthesis of Vitamin B6-type Compounds

  • Sabrina M. Austin
  • Thomas G. Waddell


Heating a dilute solution of NH3 and glycoaldehyde gives a large family of pyridines substituted with the same functional groups as occur in the forms of vitamin B6. Thus, vitamin B6-like molecules could have been present on the early Earth and could have been available for catalysis of primitive transamination reactions. Ethanolamine and N-methylethanolamine are also formed as major products. These are choline-like molecules, the latter of which is apparently formed by a prebiotic methylation process.


Methylation Organic Chemistry Catalysis Geochemistry Pyridine 
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Copyright information

© Kluwer Academic Publishers 1999

Authors and Affiliations

  • Sabrina M. Austin
    • 1
  • Thomas G. Waddell
    • 1
  1. 1.Department of ChemistryUniversity of Tennessee at ChattanoogaChattanoogaU.S.A.

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