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Plant Molecular Biology

, Volume 36, Issue 1, pp 1–10 | Cite as

Plant O-methyltransferases: molecular analysis, common signature and classification

  • Ragai K. Ibrahim
  • Anne Bruneau
  • Brigitte Bantignies
Article

Abstract

Comparative analysis of the predicted amino acid sequences of a number of plant O-methyltransferase cDNA clones show that they share some 32–71% sequence identity, and can be grouped according to the different compounds they utilise as substrates. Five highly conserved regions are proposed as a signature for plant O-methyltransferases, two of which (regions I and IV) are believed to be involved in S-adenosyl-L-methionine and metal binding, respectively. The glycine-rich signature regions include a 36 amino acid domain which is located in the mid-terminal section of the carboxy terminus of most O-methyltransferase sequences. Cladistic analysis of the amino acid sequences suggests that plant O-methyltransferases may have arisen from common ancestral genes that were driven by different structural and/or functional requirements, and whose descendants segregated into different biochemical species. A comprehensive classification of plant O-methyltransferases is proposed following the guidelines of the Commission of Plant Gene Nomenclature.

O-Methyltransferase molecular analysis signature classification 

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Copyright information

© Kluwer Academic Publishers 1998

Authors and Affiliations

  • Ragai K. Ibrahim
    • 1
  • Anne Bruneau
    • 2
  • Brigitte Bantignies
    • 1
  1. 1.Plant Biochemistry Laboratory, Department of BiologyConcordia UniversityMontréal (Canada
  2. 2.Institut de recherche en biologie végétaleUniversité de MontréalMontréal (Canada

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