Expression of epithelial cadherin and cavernous sinus invasion in human pituitary adenomas
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- Kawamoto, H., Mizoue, T., Arita, K. et al. J Neurooncol (1997) 34: 105. doi:10.1023/A:1005709014239
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Pituitary adenomas generally are regarded as benign tumors,although some invade the cavernous sinus and recur.We examined the epithelial cadherin (E-CD) expression in30 pituitary adenomas (6 with cavernous sinus invasionand 24 without). Immunoreactivity of E-CD were foundin all pituitary adenomas but they were veryvarious. The presence of an association between E-CDexpression and cavernous sinus invasion was assessed. Therewere no significant differences in E-CD expression betweeninvasive and noninvasive adenomas. These results suggest thatE-CD expression is not associated with cavernous sinusinvasion in pituitary adenomas.