Biotechnology Letters

, Volume 22, Issue 11, pp 931–936 | Cite as

Enhancement of chrysogenin production in cultures of Penicillium chrysogenum by uronic acid oligosaccharides

  • E. Asilonu
  • C. Bucke
  • T. Keshavarz

Abstract

Additions of 50 to 100 μg of acid-hydrolysed alginate oligosaccharides ml−1 and enzyme-hydrolysed pectin oligosaccharides to 24- to 48-h cultures of Penicillium chrysogenum, ATCC 9480, led to enhanced production of chrysogenin by over 30 to 40% in shaken flasks and bioreactors. Some of the oligosaccharides also promoted biomass formation but were not used as a carbon source.

chrysogenin elicitors enhancement oligosaccharides Penicillium chrysogenum 

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Copyright information

© Kluwer Academic Publishers 2000

Authors and Affiliations

  • E. Asilonu
    • 1
  • C. Bucke
    • 1
  • T. Keshavarz
    • 1
  1. 1.Fungal Biotechnology Group, Biotechnology DepartmentUniversity of WestminsterLondon UK

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