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Biotechnology Letters

, Volume 21, Issue 8, pp 663–667 | Cite as

Economic improvement of the fermentative production of gallidermin by Staphylococcus gallinarum

  • Markus Kempf
  • Uwe Theobald
  • Hans-Peter Fiedler
Article

Abstract

Gallidermin production by Staphylococcus gallinarum was optimal using a new developed medium consisting of 50 g yeast extract l−1, 45 g CaCl2 l−1 and 5 g maltose l−1. Medium optimisation led to the cost of the medium decreasing by 93% compared to the previously used medium and in addition gained a higher product yield. A scale-up of the process based on the new medium was successfully tested up to a working volume of 200 l.

antibiotic gallidermin process optimisation Staphylococcus gallinarum 

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Copyright information

© Kluwer Academic Publishers 1999

Authors and Affiliations

  • Markus Kempf
    • 1
  • Uwe Theobald
    • 1
  • Hans-Peter Fiedler
    • 1
  1. 1.Mikrobiologisches InstitutUniversität TübingenTübingenGermany

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