Skip to main content
SpringerLink
Log in

CASE REPORT: Severe and Relapsing Upper Gastrointestinal Bleeding in a Patient with Glanzmann's Thrombasthenia

  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

REFERENCES

  1. Glanzmann E: Hereditare hamorrhagische thromboasthenie: ein beitrag zur pathologie der blut plattchen. J Kinderkr 88:1-13, 1918

    Google Scholar 

  2. Nurder AT, Caen JP: An abnormal platelet glycoprotein pattern in three cases of Glanzmann's thrombasthenia. Br J Haematol 28:253-260, 1974

    Google Scholar 

  3. Caen JP: Glanzmann's thrombasthenia. Baillieres Clin Haematol 2:609-625, 1989

    Google Scholar 

  4. Phillips DR, Charo IF, Parise LV, Fitzgerald LA: The platelet membrane glycoprotein IIb-IIIa complex. Blood 71:831-843, 1988

    Google Scholar 

  5. George JN, Nurden AT, Phillips DR: Molecular defects in interactions of platelets with the vessel wall. N Engl J Med 311:1084-1098, 1984

    Google Scholar 

  6. George JN: Disorders of hemostatis and thrombosis. In Internal Medicine. JH Stein (ed). Boston, Little, Brown, 1990, p 1030

    Google Scholar 

  7. Nurden AT: Congenital abnormalities of platelet membrane glycoproteins. In Platelet Immunobiology. Molecular and Clinical Aspects. TJ Kunicki, JN George (eds). Philadelphia, Lippincott 1989, p 63

    Google Scholar 

  8. Bray PF, Shuman MA: Molecular analysis of the genes for platelet glycoproteins IIb and IIIa in a normal population and a family with Glanzmann thrombasthenia. Blood 72:317A, 1988

    Google Scholar 

  9. Loftus JC, O'Toole TE, Plow EF, Ginsberg MH: Identification of a GP IIb-IIIa mutation in a Glanzmann variant associated with loss of RGD binding function. Blood 74:58A, 1989

    Google Scholar 

  10. George JN, Caen JP, Nurden AT: Glanzmann's thrombasthenia: The spectrum of clinical disease. Blood 75(7):1383-1395, 1990

    Google Scholar 

  11. Awidi A: Delivery of infants with Glanzmann's thrombasthenia and subsequent blood transfusion requirements: A follow-up of 39 patients. Am J Hematol 40:1-4, 1992

    Google Scholar 

  12. Bennet J, Kolodziej M: Disorders of platelet function. Dis Mon 38:577-631, 1992

    Google Scholar 

  13. Culbertson MC Jr: Epistaxis, In Pediatric Otolaryngology. CD Bluestone, SE Stool (eds). Philadelphia, Saunders, 1983, p 719

    Google Scholar 

  14. Hardisty RM, Dormandy KM, Hutton RA: Thrombasthenia: Studies of three cases. Br J Haematol 10:371, 1964

    Google Scholar 

  15. Stormorken H, Gogstad GO, Solum NO, Pande H: Diagnosis of heterozygotes in Glanzmann's thrombasthenia. Thromb Haemost 48:217-221, 1982

    Google Scholar 

  16. Weiss HJ, Turitto VT, Bamgartner HR: Platelet adhesion and thrombus formation on subendothelium in platelets deficient in glycoprotein IIb/IIIa, Ib, and storage granules. Blood 67:322-330, 1986

    Google Scholar 

  17. Weiss HJ, H Awiger J, Ruggeri ZM, Turitto VT, Thiagarajan P, Hofmann T: Fibrinogen independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb/IIIa complex at high shear rates. J Clin Invest 83:288-297, 1989

    Google Scholar 

  18. Jennings LK, Wang WC, Jackson LW, et al: Hemostasis in Glanzmann's thrombasthenia: GT platelets interfere with the aggregation of normal platelet. Am J Pediatr Hematol Oncol 13:84-90, 1991

    Google Scholar 

  19. Laursen B, Jacobsen SEH, Taaning E, et al: Transfusion problems in patients with Glanzmann's thrombasthenia. Eur J Haematol 49:143-144, 1992

    Google Scholar 

  20. Bellucci S, Devigia A, Gluckmann E, et al: Complete correction of Glanzmann's thrombasthenia by allogenic bone marrow transplantation. Br J Haematol 59:635-641, 1985

    Google Scholar 

  21. McColl MD, Gibson BES: Sibling allogenic bone marrow transplantation in a patients with type I Glanzmann's thrombasthenia. Br J Haematol 99:58-60, 1997

    Google Scholar 

  22. Calva-Rodriguez R, Mejia-Dominguez AM, Pandzich-Arapov S: Ulcera gastrica cronica en un nino con trombastenia de Glanzmann. Utilidad de la prostaglandina E2. Bol Med Hosp Infant Mex 47:653-655, 1990

    Google Scholar 

  23. Agarwal MB, Agarwal UM, Viswanathan C, Bhava AA, Billa V: Glanzmann's thrombasthenia. Indian Pediatrics 29:837-841, 1992

    Google Scholar 

  24. Nounou R, Spence D: Glanzmann's thrombasthenia with mild von Willebrand's disease. J Clin Phathol 46:1134-1136, 1993

    Google Scholar 

  25. Gruel Y, Pacouret G, Bellucci S, Caen J: Severe proximal deep vein thrombosis in a Glanzmann thrombasthenia variant successfully treated with a low molecular weight heparin. Blood 90:888-890, 1997

    Google Scholar 

  26. De Rose JJ, Diamond S, Bergmann K: Spontaneous duodenal hematoma in a patients with Glanzmann's thrombasthenia. J Pediatr Surg 32:1341-1343, 1997

    Google Scholar 

  27. Leach M, Makris M, Hampton KK, Preston FE: Norethisterone therapy for bleeding due to gastrointestinal telangiectases in Glanzmann's thrombasthenia. Br J Haematol 100:594-596, 1998

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy

    C. Calabrese, G. Di Febo, A. Areni, M.C. Morelli, C. Scialpi, G. Brandi & M. Miglioli

Authors
  1. C. Calabrese
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Di Febo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. Areni
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. M.C. Morelli
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. C. Scialpi
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. G. Brandi
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. M. Miglioli
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Calabrese, C., Di Febo, G., Areni, A. et al. CASE REPORT: Severe and Relapsing Upper Gastrointestinal Bleeding in a Patient with Glanzmann's Thrombasthenia. Dig Dis Sci 45, 633–636 (2000). https://doi.org/10.1023/A:1005478114897

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1005478114897

Search

Navigation