Digestive Diseases and Sciences

, Volume 45, Issue 4, pp 809–818

Upper Gastrointestinal Symptoms in North America

  • Lori Frank
  • Leah Kleinman
  • Dara Ganoczy
  • Kenneth Mcquaid
  • Sheldon Sloan
  • Andrew Eggleston
  • Gervais Tougas
  • Christina Farup
Article

Abstract

The aim of this study was to determine the prevalence of upper gastrointestinal symptoms (UGIS) in a general population and quantify the relationship of those symptoms to health-care utilization and quality of life. In-person interviews were conducted with 2056 United States and Canadian residents selected at random. Subjects reported frequency and severity for 11 symptoms, prescription and over-the-counter medication use, primary care and specialty physician visits in prior three months, and completed the Psychological General Well-Being Scale. For analyses, subjects were classified into four mutually exclusive symptom groups: gastroesophageal reflux disease (GERD) -like, GERD plus motility-like (GERD+), ulcerlike, and motility-like. Of the total sample, 51.4% reported the occurrence of at least one UGIS in the prior three months. Subjects in the GERD+ and ulcer groups used more prescription medications and were more likely to see a physician about the symptoms (P < 0.001). Subjects with symptoms demonstrated poorer quality of life compared to subjects with no symptoms. The prevalence of UGIS in the general population is high and symptoms are associated with significant health-care utilization and poorer quality of life.

gastrointestinal symptoms ulcer gastroesophageal reflux disease health-care utilization quality of life 

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Copyright information

© Plenum Publishing Corporation 2000

Authors and Affiliations

  • Lori Frank
    • 1
    • 2
    • 3
    • 4
    • 5
  • Leah Kleinman
    • 1
    • 2
    • 3
    • 4
    • 5
  • Dara Ganoczy
    • 1
    • 2
    • 3
    • 4
    • 5
  • Kenneth Mcquaid
    • 1
    • 2
    • 3
    • 4
    • 5
  • Sheldon Sloan
    • 1
    • 2
    • 3
    • 4
    • 5
  • Andrew Eggleston
    • 1
    • 2
    • 3
    • 4
    • 5
  • Gervais Tougas
    • 1
    • 2
    • 3
    • 4
    • 5
  • Christina Farup
    • 1
    • 2
    • 3
    • 4
    • 5
  1. 1.Center for Health Outcomes ResearchMEDTAP International, Inc.Bethesda
  2. 2.Gastroenterology SectionVeteran's Administration Medical CenterSan Francisco
  3. 3.Janssen Research FoundationTitusville
  4. 4.Janssen Ortho Inc.North York, OntarioCanada; and
  5. 5.Intestinal Disease Research Programme, Division of GastroenterologyMcMaster UniversityHamilton, OntarioCanada

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