Biotechnology Letters

, Volume 21, Issue 3, pp 193–197

Production of poly(4-hydroxybutyric acid) by fed-batch cultures of recombinant strains of Escherichia coli

  • Shuishan Song
  • Silke Hein
  • Alexander Steinbüchel
Article

DOI: 10.1023/A:1005451810844

Cite this article as:
Song, S., Hein, S. & Steinbüchel, A. Biotechnology Letters (1999) 21: 193. doi:10.1023/A:1005451810844

Abstract

A recombinant strain of Escherichia coli was used to produce poly(4-hydroxybutyric acid), P(4HB), homopolyester by fed-batch culture in M9 mineral salts medium containing glucose and 4-hydroxybutyric acid as carbon sources. The final cell dry weight, P(4HB) concentration and P(4HB) content were 12.6 g/l, 4.4 g/l, and 36% of cell dry weight, respectively, in a 27-l stirred and aerated fermenter after 60 h of fed-batch fermentation at constant pH.

poly(4-hydroxybutyric acid) 4-hydroxybutyric acid polyester recombinant E. coli 

Copyright information

© Kluwer Academic Publishers 1999

Authors and Affiliations

  • Shuishan Song
    • 1
  • Silke Hein
    • 1
  • Alexander Steinbüchel
    • 1
  1. 1.Institut für MikrobiologieWestfalische Wilhelms-Universität MünsterMünster

Personalised recommendations