Genetica

, Volume 108, Issue 1, pp 47–51 | Cite as

Visualization of Pathogenicity Regions in Bacteria

  • Carsten Friis
  • Lars Juhl Jensen
  • David W. Ussery
Article

Abstract

We show here how pathogenicity islands can be analysed using GenomeAtlases, which is a method for visualising repeats, DNA structural characteristics, and base composition of chromosomes and plasmids. We have applied this method to the E. coliplasmid pO157, and the Y. pestisplasmid pPCP1. In both cases pathogenic genes were shown to differ in A+Tcontent and structural properties. Furthermore, examination of an antibiotic resistance gene cluster from S. typhimuriumshowed that the same was true for genes encoding antibiotic resistance.

base composition Escherichia coli pathogenicity islands Salmonella typhimuriumDT104 Yersenia pestis 

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Copyright information

© Kluwer Academic Publishers 2000

Authors and Affiliations

  • Carsten Friis
    • 1
  • Lars Juhl Jensen
    • 1
  • David W. Ussery
    • 2
  1. 1.The Technical University of DenmarkLyngbyDenmark
  2. 2.Center for Biological Sequence Analysis, Department of BiotechnologyThe Technical University of DenmarkLyngbyDenmark

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