Child Psychiatry and Human Development

, Volume 31, Issue 2, pp 139–151 | Cite as

Panic Disorder in Clinically Referred Children and Adolescents

  • Gabriele Masi
  • Letizia Favilla
  • Maria Mucci
  • Stefania Millepiedi


Prevalence, phenomenology, comorbidity, functional impairment and familial correlates of juvenile panic disorder (PD) are described in this study. A clinical interview (Diagnostic Interview for Children and Adolescents-Revised) was administered to 220 children and adolescents consecutively referred to a Division of Child Neurology and Psychiatry. 23 subjects (10.4%), aged 7 to 18 years, fulfilled DSM-IV criteria for PD. Reported panic symptoms are described, according to gender and chronological age. High comorbidity with generalized anxiety disorder (74%) and depression (52%) was noted. Agoraphobia (56%) and other phobias (56%) were significantly more frequent than in two control groups of subjects with generalized anxiety disorder and with depression. Antecedent and/or associated separation anxiety disorder was reported in 73% of the patients. Functional impairment, assessed with a specific diagnostic instrument (Children's Global Assessment Scale) was significantly greater in PD patients than in depressed or anxious patients. 90% of patients had at least one parent with an anxiety disorder, 52% had one parent with depressive disorder, 33% had one parent with drug treated PD.

Panic Disorder Children Adolescents Generalized Anxiety Disorder Depression 


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Copyright information

© Human Sciences Press, Inc. 2000

Authors and Affiliations

  • Gabriele Masi
    • 1
  • Letizia Favilla
    • 2
  • Maria Mucci
    • 2
  • Stefania Millepiedi
    • 2
  1. 1.IRCCS Stella Maris, Division of Child Neurology and PsychiatryUniversity of PisaCalambrone (PI)Italy
  2. 2.Division of Child Neurology and PsychiatryUniversity of Pisa; IRCCS Stella MarisCalambrone, Pisa

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