Abstract
—The effect of four biologically active and naturally occurring plant quinones, namely maesanin, maesaquinone, embelin and juglone on the respiration of mitochondria isolated from Glossina morsitans morsitans, Schistoscerca gregaria and Periplaneta americana was investigated. The rate of oxygen consumption by the mitochondria was measured using an oxygen electrode. Maesanin inhibited the mitochondrial electron transport chain at a level before cytochrome C whereas maesaquinone and embelin uncoupled the mitochondria. Juglone inhibited respiration in G. m. morsitans mitochondria and uncoupled those of S. gregaria and P. americana.
Résumé
—L’effet de 4 quinones végétales et actives biologiquements, notament maesanine, maesaquinone, embeline et juglone, a été étudié sur les mitochondries respiratoires isolées de Glossina morsitans morsitans, Schistocerca gregaria et Periplaneta americana. Le taux de consommation d’oxygène par les mitochondries a été mésuree à l’aide d’un electrode à oxygène. La maesanine a inhibé la chaine de transport de l’électron des mitochondries à un stade avant le cytochrome C tandis que le maesaquinone et l’embeline ont fait détacher la membrane mitochondriale. Le juglone a inhibé la respiration chez les mitochondries de G. m. morsitans et fait détacher celles de S. gregaria et P. americana.
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References
Addison A. W., Cullen W. R., Dolphin D. and Janes B. R. (1977) Biological Aspects of Inorganic Chemistry. Wiley Interscience, New York, Sydney, Toronto.
Burseil E. (1975) Substrates of oxidative metabolism in dipteran flight muscle. Comp. Biochem. Physiol. 52, 235–238.
Bursell E., Billing K. C, Hagrove J. W., McCabe C. T. and Slack E. (1974) Metabolism of blood meal in tsetse flies. Acta Trop. 31, 297–320.
Chander H. and Ahmed S. A. (1985) Efficacy of natural embelin against the red flour beetle, Tribolium castaneum (Herbst). Insect Sci. Applic. 6, 217–220.
Chander H. and Ahmed S. A. (1987) Laboratory evaluation of natural embelin as a grain protectant against some insect pests of wheat in storage. J. Stored Prod. Res. 23, 41–46.
Dale I. R. and Green way P. J. (1961) Kenyan Trees and Shrubs Buchanan’s Kenya Estates Ltd. Nairobi, 329 pp.
Deshmukh S. D. and Borle M. N. (1975) Studies on the insecticidal properties of indigenous products. Indian J. Ent. 37, 11–18.
Ernster L. (1967) D.T. Diaphorase. In Methods in Enzymology (Edited by Estabrook R. W. and Pullman E. N.), Vol. 10, pp. 309–314. Academic Press, New York and London.
Huang P., Chen W. and Hu Y. (1980) Studies on antituberculosis constituents from Ardisia japonica Senth. China Inst. Bot. Yao Hsueh Tung Pao, 15, 39.
Jacob E. E. and Crane F. L. (1960) Phosphorylation coupled to electron transport mediated by short chain derivatives of coenzymes A. Biochem. Biophys. Res. Commun. 2, 218–221.
Lehninger A. L. (1915) Biochemistry, Third Edition. Worth Publishers, Inc. New York.
Mabberley D. J. (1987) The Plant Book. Cambridge University Press, Melbourne, Australia.
Midiwo J. O., Arot L.M. and Mbakaya L. (1988) Distribution of benzoquinone pigments in Kenyan Myrsinacea. Bull. Chem. Soc. Ethiop. 2, 83–85.
Njagi E. M. N. (1987) Transport and metabolism of proline and tricarboxylic acid cycle intermediate by the mitochondria of the tsetse fly Glossina morsitans. M.Sc. Thesis, University of Nairobi.
Ogawa H. and Natoris S. (1968) Hydroxybenzoquinones from Myrsinaceae. Plants—II. Phytochem. 7, 773–779.
Rao D. V., Rao V. V. and Raghunada P. (1985) Studies on embelin Part III. Synthesis and biological activity of some anthranilic acid ester derivatives of embelin and embelin-di-o-methyl ether. Indian J. Chem. 24, 988–991.
Richard L. C. and Wang J. H. (1970) Evidence of a phosphorylated intermediate in mitochondria oxidative phosphorylation. Biochem. Biophys. Res. Commun. 38, 848–854.
Shar V., Sunder R. and De Souza N. J. (1984) Chornemorphine and rapanone antiparasite agents from plant source. J. Nat. Prod. 50, 730–731.
Slater E. C. (1950) Application of inhibitors and uncouplers for a study of oxidative phosphorylation. In Methods in Enzymology (Edited by Estabrook R. W. and Pullman E. N.), Vol. 10, pp. 48–57. Academic Press, New York and London.
Webb J. L. (1966) Quinones. In Enzyme and Metabolic Inhibitors (Edited by Webb J. L.), Vol. 3, pp. 445–594. Academic Press, New York.
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Magiri, E.N., Konji, V.N., Makawiti, D.W. et al. Effect of Plant Quinones on Insect Flight Muscle Mitochondria. Int J Trop Insect Sci 16, 183–189 (1995). https://doi.org/10.1017/S1742758400017094
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DOI: https://doi.org/10.1017/S1742758400017094