Abstract
Identification and taxonomy of the genus Leishmania is considered in brief, drawing on existing review articles. A fully-referenced synopsis of clinical, epidemiological, biological, immunological and biochemical criteria and methods used for typing leishmanial parasites is given and discussed. Classical and modern approaches are compared. Leishmanial phylogeny, the value of numerical taxonomy and the possibility of sexual recombination in leishmanial organisms are also considered.
Résumé
L’dentification et la taxonomie dans le genre Leishmania sont rappelés brièvement, pour attirer l’attention sur les revues et les articles existents. Les critères et les méthodes cliniques épidémiologiques, biologiques, immunologiques et biochimiques utilisés pour typer ces parasites sont résumés dans un tableau synoptique et discuté. Les approaches classiques et modernes sont comparées entre elles. La phylogénie des Leishmania, l’utilité de la taxonomie numérique et la possibilité de recombinaison sexualle dans les Leishmania sont également discutées.
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References
Abdalla R. E. (1982) Parasites in Sudanese cutaneous and mucosal leishmaniasis. Ann. trop. Med. Parasit. 76, 299–307.
Adanson M. (1763) Familles des Plants I. Vincent, Paris.
Adler S. (1932) Observations on two races of L. tropica. In. The Emanual Libman Anniversary Volumes, pp. 1–6. International Press, New York.
Adler S. (1962) The behaviour of a lizard leishmania in hamsters and baby mice. Rev. Inst. Med. trop. São Paulo 4, 61–64.
Adler S. (1964) Leishmania. Adv. Parasit. 2, 35–96.
Adler S. and Gunders A. (1964) Immunity to Leishmania mexicana following spontaneous recovery from oriental sore. Trans. R. Soc. trop. Med. Hyg. 58, 274–277.
Adler S. and Theodor O. (1926) The identity of Leishmania tropica Wright, 1903 and Herpetomonas papatasii Adler, 1925. Ann. trop. Med. Parasit. 20, 355–364.
Afchain D., Le Ray D., Capron A. and Jadin J. (1973) Analyse antigénique comparée, par immunoélectrophorèse, des formes de culture de Trypanosoma (Schizotrypanum) cruzi, Trypanosoma (Trypanoozoon) brucei et Leishmania donovani. Conséquences taxonomiques et diagnostiques. Protistologica 9, 213–220.
Arnot D. E. and Barker D. C. (1981) Biochemical identification of cutaneous leishmanias by analysis of kinetoplast DNA. IL Sequence homologies in Leishmania kDNA. Mol. Biochem. Parasit. 3, 47–56.
Barker D. C. and Arnot D. E. (1981) Biochemical identification of cutaneous leishmanias by analysis of kinetoplast DNA. I. Ultrastructural and buoyant density analysis. Mol. Biochem. Parasit. 3, 33–46.
Barker D. C., Arnot D. E. and Butcher J. (1982) DNA characterization as a taxonomic tool for identification of kinetoplastic flagellate protozoons. In Biochemical Characterization of Leishmania (Edited by Chance M. L. and Walton B. C.), pp. 139–180. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva.
Barker D. C. and Butcher J. (1983) The use of DNA probes in the identification of leishmanias: discrimination between isolates of Leishmania mexicana and L. braziliensis complexes. Trans. R. Soc. trop. Med. Hyg. 77, 285–297.
Beach R. and Mebrahtu Y. (1985) Rapid enzymological identification of leishmanial isolates in Kenya. Trans. R. Soc. trop. Med. Hyg. 79, 445–447.
Belazzoug S. (1982) Isoenzyme characterization of Leishmania spp. from Algeria. In Biochemical Characterization of Leishmania. (Edited by Chance M. L. and Walton B. C.), pp. 99–104. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva.
Bray R. S. (1974) Leishmania. A. Rev. Microbiol. 28, 189–217.
Bray R. S., Ashford R. W. and Bray M. A. (1973) The parasite causing cutaneous leishmaniasis in Ethiopia. Trans. R. Soc. trop. Med. Hyg. 67, 345–347.
Bray R. S. and Bryceson A. D. M. (1969) Studies on the immunology and serology of leishmaniasis. VIII. The identity of strains of Leishmania from Ethiopian diffuse cutaneous leishmaniasis. Trans. R. Soc. trop. Med. Hyg. 63, 524–527.
Bray R. S. and Rahim G. A. F. (1969) Studies on the immunology and serology of leishmaniasis. VII. Serotypes of Leishmania tropica. Trans. R. Soc. trop. Med. Hyg. 63, 383–387.
Chance M. L. (1976) DNA relationships in the genus Leishmania. In Biochemistry of Parasites and Host-Parasite Relationships (Edited by Van den Bossche H.), pp. 229–235. Elsevier/North-Holland Biomedical Press, Amsterdam.
Chance M. L. (1979) The identification of Leishmania. In Problems in the Identification of Parasites and Their Vectors (Edited by Taylor A. E. R. and Muller R.), pp. 55–74. Blackwell Scientific Publications, Oxford.
Chance M. L. (1984) Experimental studies of visceral and cutaneous leishmaniasis. In Recent Advances in Tropical Medicine (Edited by Gilles H. M.), pp. 102–113. Churchill Livingstone, London.
Chance M. L., Gardener P. J. and Peters W. (1977) Biochemical taxonomy of Leishmania as an ecological tool. Colloques Internationaux du C.N.R.S., No. 239, Ecologie des Leishmanioses, pp. 53–62.
Chance M. L., Peters W. and Shchory L. (1974) Biochemical taxonomy of Leishmania I: Observations on DNA. Ann. trop. Med. Parasit. 68, 307–316.
Chance M. L., Schnur L. F., Thomas S. L. and Peters W. (1978) The biological and serological taxonomy of Leishmania from the Aethiopian zoogeographical region of Africa. Ann. trop. Med. Parasit. 72, 533–542.
Chance M. L. and Walton B. C. (1982) Biochemical characterization of Leishmania. UNDP/World Bank/Who Special Programme for Research and Training in Tropical Diseases, Geneva.
Croft S. L. and Schnur L. F. (1979) The Noguchi-Adler phenomenon: an ultrastructural study of the effect of homologous antisera on the growth of promastigotes of Leishmania braziliensis braziliensis and L. hertigi hertigi. Ann. trop. Med. Parasit. 73, 536–546.
Decker-Jackson J. E., Schrot J. and Levin G. V. (1977) Identification of Leishmania spp. by radiorespirometry. J. Protozool. 24, 463–470.
Decker-Jackson J. E. and Tang D. B. (1982) Identification of Leishmania spp. by radiorespirometry II: A statistical method of data analysis to evaluate the reproducibility and sensitivity of the technique. In Biochemical Characterization of Leishmania (Edited by Chance M. L. and Walton B. C), pp. 205–245. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva.
Dedet J.-P. (1977) Les leishmanioses en Afrique du Nord. Bull. Inst. Past. 77, 49–82.
Divon-Rozytcka C. (1963) A serological comparison between three strains of Leishmania, L. tropica, L. tropica major and L. tropica minor. M.Sc thesis, Hebrew University, Jerusalem.
Ebert F. (1973) Charakterisierung von Leishmania donovani-Stämmen mit der Disk-Elektrophoorese. Z. Tropenmed. Parasit. 24, 517–524.
Ebert F. (1974a) Elektrophoretische Untersuchungen an Leishmania tropica Stämmen. Z. Tropenmed. Parasit. 25, 49–53.
Ebert F. (1974b) Verleichende elektrophoretische Untersuchungen an Erreger-Stämmen der cutanen Leishmaniase der Neuen Welt und ihre Beziehungen zu Leishmania donovani und L. tropica. Z. Tropenmed. Parasit. 25, 259–266.
Elbihari S., Kawasmeh Z. A. and Al Naiem A. M. (1984) Possible reservoir host(s) of zoonotic cutaneous leishmaniasis in Al-Hassa oasis, Saudi Arabia. Ann. trop. Med. Parasit. 78, 543–545.
Fish W. R., Holz G. G. Jr, Beach D. H., Owen E. and Anekwe G. E. (1981) The cyclopropane fatty acid of trypanosomatids. Mol. Biochem. Parasit. 3, 103–115.
Gardener P. J. (1977) Taxonomy of the genus Leishmania: A review of nomenclature and classification. Trop. Dis. Bull. 74, 1069–1088.
Gardener P. J., Chance M. L. and Peters W. (1974) Biochemical taxonomy of leishmania II: Electrophoretic variation of malate dehydrogenase. Ann. trop. Med. Parasit. 68, 317–325.
Gardener P. J., Shchory L. and Chance M. L. (1977) Species differentiation in the genus Leishmania by morphometric studies with the electron microscope. Ann. trop. Med. Parasit. 71, 147–155.
Godfrey D. G. (1984) Molecular biochemical characterisation of human parasites. In Recent Advances in Tropical Medicine (Edited by Gilles H. M.), pp. 289–319. Churchill Livingston, London.
Greenblatt C. L., Slutzky G. M., de Ibarra A. and Snary D. (1983) Monoclonal antibodies for the serotyping of Leishmania strains. J. clin. Microbiol. 18, 191–193.
Gueugnot J., Guillot M., Damez M. and Coulet M. (1984) Identification and taxonomy of human and animal leishmanias by lectinmediated agglutination. Acta trop. 41, 135–143.
Handman E., Hocking R. E., Mitchell G. F. and Spithill T. W. (1983) Isolation and characterization of infective and non-infective clones of Leishmania tropica. Mol. Biochem. Parasit. 7, 111–126.
Harris H. (1980) The Principles of Human Biochemical Genetics, 3rd edn. Elsevier/North Holland Biomedical Press, Amsterdam.
Heisch R. B. (1958) On Leishmania adleri sp. nov. from lacertid lizards (Latastia sp.) in Kenya. Ann. trop. Med. Parasit. 52, 68–71.
Hernández A. G. (1982) Lectins as a tool in parasite research. In Biochemical Characterization of Leishmania (Edited by Chance M. L. and Walton B. C.), pp. 181–196. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva.
Hill L. R. (1984) Numerical taxomomy: general principles and problems of application. In New Approaches to the Identification of Parasites and Their Vectors, Tropical Diseases Research Series Vol. 5 (Edited by Newton B. M. and Michal F.), pp. 35–49. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva.
Holz G. G. Jr and Beach D. H. (1982) Catagorization of Old World leishmaniasis by cyclopropane fatty acid content of cultured promastigotes. In Biochemical Characterization of Leishmania (Edited by Chance M. L. and Walton B. C), pp. 197–203. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva.
Hommel M. (1978) The genus Leishmania: Biology of the parasites and clinical aspects. Bull. Inst. Past. 75, 5–102.
Jackson P., Wohlieter J. A., Jackson J. E., Sayles P., Diggs C. L. and Hockmeyer W. T. (1984) Restriction endonuclease analysis of Leishmania kinetoplast DNA characterizes parasites responsible for visceral and cutaneous disease. Am. J. trop. Med. Hyg. 33, 808–819.
Jacobson R. L., Slutzky G. M., Greenblatt C. L. and Schnur L. F. (1982) Surface reaction of Leishmania I. Lectinmediated agglutination. Ann. trop. Med. Parasit. 76, 45–52.
Jaffe C. L. and McMahon-Pratt D. (1983) Monoclonal antibodies specific for Leishmania tropica I. Characterization of antigens associated with stage- and speciesspecific determinants. J. Immun, 131, 1987–1993.
Jenni L., Marti S. and Betschart B. (1984) Simultaneous cyclical transmission of Trypanosoma brucei gambiense and Trypanosoma brucei brucei. In Abstracts of the Fourth European Multicolloquium of Parasitology (Izmir), p. 97.
Jenni L., Marti S., Schweizer J. and Betschart B. (1985) Formation of hybrid Trypanosoma (T.) brucei in Glossina. In Abstracts of the Seventh International Congress of Protozoology (Nairobi), p. 139.
Kellina O. I. (1962) On the dimensions of Leishmania Tropica major and Leishmania tropica minor. Medskaya Parazit. 31, 716–718.
Kirk R. (1949) The differentiation and nomenclature of Leishmania. Parasitology 39, 263–273.
Kligler I. J. (1925) The culture and serological relationships of Leishmania. Trans. R. Soc. trop. Med. Hyg. 19, 330–335.
Kohanteb J., Ardehali S. and Rezai H. R. (1980) Studies on antigenic relationships of Leishmania promastigotes by electroimmunodiffusion and crossed electroimmunodiffusion tests. Trans. R. Soc. trop. Med. Hyg. 74, 582–584.
Kozhevnikov P. V. (1963) Two nosological forms of cutaneous leishmaniasis. Am. J. trop. Med. Hyg. 12, 719–724.
Kreutzer R. D. (1982) The cellulose acetate electrophoresis method for isozyme characterization of Leishmania isolates. In Biochemical Characterization of Leishmania (Edited by Chance M. L. and Walton B. C.), pp. 81–85. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva.
Kreutzer R. D. and Christensen H. A. (1980) Characterization of Leishmania spp. by isoenzyme electrophoresis. Am. J. trop. Med. Hyg. 29, 199–208.
Kreutzer R. D. and Souraty N. (1984) Accurate identification of Leishmania isolates by study of three enzymes. In Abstracts of the 33rd Annual Meeting of the American Society of Tropical Medicine and Hygiene, Baltimore.
Lainson R. and Bray R. S. (1966) Studies on the immunology and serology of leishmaniasis. II. Cross-immunity experiments among different forms of American cutaneous leishmaniasis in monkeys. Trans. R. Soc. trop. Med. Hyg. 60, 526–532.
Lainson R. and Shaw J. J. (1966) Studies on the immunology and serology of leishmaniasis. III. On the crossimmunity between Panamanian cutaneous leishmaniasis and Leishmania mexicana infection in man. Trans R. Soc. trop. Med. Hyg. 60, 533–535.
Lainson R. and Shaw J. J. (1970) Leishmaniasis in Brazil. V. Studies on the epidemiology of cutaneous leishmaniasis in Mato Grosso State, and observations on two distinct strains of Leishmania isolated from man and forest animals. Trans. R. Soc. trop. Med. Hyg. 64, 654–667.
Lainson R. and Shaw J. J. (1979) The role of animals in the epidemiology of South American leishmaniasis. In Biology of the Kinetoplastida, Vol. 2 (Edited by Lumsden W. H. R. and Evans D. A.), pp. 1–116. Academic Press, London.
Lanham S. M. (1982) Kits for isoenzyme characterization of Leishmania isolates in the field. In Biochemical Characterization of Leishmania (Edited by Chance M. L. and Walton B. C), pp. 87–98. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva.
Lanham S. M., Grendon J. M., Miles M. A., Povoa M. M. and Almeida de Souza A. A. (1981) A comparison of electrophoretic methods for isoenzyme characterization of trypanosomatids. I: Standard stocks of Trypanosoma cruzi zymodemes from northeast Brazil. Trans. R. Soc. trop. Med. Hyg. 75, 742–750.
Lanotte G., Rioux J. A., Maazoun R., Pasteur N., Pratlong F. and Lepart J. (1981) Application de la méthode numérique à la taxonomie du genre Leishmania Ross, 1903. A propos de 146 souches originaires de l’Ancine Monde. Utilisation des allozymes. Corollaires épidémiologiques et phyletiques. Amis Parasit, hum. comp. 56, 576–592.
Le Blancq S. M., Belehu A. and Peters W. (1986a) Leishmania in the Old World: 3. The distribution of L. aethiopica zymodemes. Trans. R. Soc. trop. Med. Hyg. In press.
Le Blancq S. M., Schnur L. F. and Peters W. (1986b) Leishmania in the Old World: I. The geographical and hostal distribution of L. major zymodemes. Trans. R. Soc. trop. Med. Hyg. In press.
Le Blancq S. M., Cibulskis R. E. and Peters W. (1986c) Leishmania in the Old World: 5. Numerical analysis of isoenzyme data. Trans. R. Soc. trop. Med. Hyg. In press.
Le Blancq S. M. and Peters W. (1986a) Leishmania in the Old World: 2. Heterogeneity among L. tropica zymodemes. Trans. R. Soc. trop. Med. Hyg. In press.
Le Blancq S. M. and Peters W. (1986b) Leishmania in the Old World: 4. The distribution of L. donovani sensu lato zymodemes. Trans. R. Soc. trop. Med. Hyg. In press.
Le Blancq S. M., Schnur L. F. and Schiein Y. (1983) An apparent association of enzymic variants of Leishmania major with specific geographical areas in Israel. Bull. Soc. Path. exot. 76, 543–548.
Le Ray D., Afchain D. and Capron A. (1977) Contributions de la connaissance des antigèns de Leishmania à l’immunologie des trypanosomatidae. Colloques Internationaux du C.N.R.S., No. 239, Ecologie des Leishmanioses, pp. 64–73.
Lumsden W. H. R. (1974) Biochemical taxonomy of Leishmania. Trans. R. Soc. trop. Med. Hyg. 68, 74–75.
Maazoun R., Lanotte G., Pasteur N., Rioux J.-A., Kennou M. F. and Pratlong F. (1981a) Écologie des leishmanioses dans le sud de la France 16. Contribution à l’analyse chimiotaxonomique des parasites de la leishmaniose viscérale méditerranéenne. A propos de 55 souches isolées en Cévennes, Côte d’Azur, Corse et Tunisie. Annls Parasit, hum. comp. 56, 131–146.
Maazoun R., Lanotte G., Rioux J.-A., Pasteur N., Killick-Kendrick R. and Pratlong F. (1981b) Signification du Polymorphisme enzymatique chez les leishmanies. A propos de trois souches hétérozygotes de Leishmania infantum Nicolle, 1908, Leishmania cf. tarentolae Wenyon, 1921 et Leishmania aethiopica Bray, Ashford and Bray, 1973. Annls Parasit, hum. comp. 56, 467–475.
Manson-Bahr P. E. C. and Winslow D. J. (1971) Cutaneous leishmaniasis. In Pathology of Protozoal and Helminthic Diseases (Edited by Marcial-Rojas R. A.), pp. 97–114. Williams & Wilkins, Baltimore.
Marques da Cuhna A. (1942) A sero-agglutinaçao das leishmanias. Memor. Inst. Oswaldo Cruz, Rio de Janeiro 37, 35–76.
Matossian-Rogers A., Lumsden W. H. R. and Dumonde D. C. (1976) Numerical Taxonomy of Leishmania I. Differentiation of four strains of Leishmania by serological tests. Immunology 31, 1–19.
McMahon-Pratt D. and David J. R. (1981) Monoclonal antibodies that distinguish between New World species of Leishmania. Nature 291, 581–583.
McMahon-Pratt D. and David J. R. (1982) Application of monoclonal antibodies specific for Leishmania species. In Biochemical Characterization of Leishmania (Edited by Chance M. L. and Walton B. C.), pp. 247–257. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva.
McMahon-Pratt D., Bennett E. and David J. R. (1982) Monoclonal antibodies that distinguish subspecies of Leishmania braziliensis. J. Immun. 129, 926–927.
Miles M. A., Lanham S. M., Souza A. A. de and Povoa M. M. (1980a) Further enzymic characters of Trypanosoma cruzi and their evaluation for strain identification. Trans. R. Soc. trop. Med. Hyg. 74, 221–237.
Miles M. A., Povoa M. M., Souza A. A. de, Lainson R. and Shaw J. J. (1980b) Some methods for the enzymic characterization of Latin American Leishmania with particular reference to L. mexicana amazonensis and subspecies of Leishmania hertigi. Trans. R. Soc. trop. Med. Hyg. 74, 243–252.
Peters W. (1981) Technologogical advances in protozoal taxonomy and systematics. In Parasitological Topics: a Presentation Volume to P. C. C. Garnham FRS on the Occasion of his 80th Birthday (Edited by Canning E. V.), pp. 200–209. Society of Protozoologists Special Publication No. 1.
Peters W. (1982) Introduction to the Workshop. In Biochemical Characterization of Leishmania (Edited by Chance M. L. and Walton B. C.), pp, 1–7. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva.
Saf’Janova V. M. and Aliev E. I. (1971) On the method for evaluation of the degree of antigenic relationship of different strains of Leishmania. Medskaya Parazit. 40, 315–321.
Saf’Janova V. M. and Aliev E. I. (1973) Comparative study of biochemical characteristics of the causal agents of zoonotic and anthroponotic cutaneous leishmaniasis in the USSR. Bull. Wld Hlth Org. 49, 499–506.
Schiein Y., Warburg A., Schnur L. F., Le Blancq S. M. and Gunders A. E. (1984) Leishmaniasis in Israel: Reservoir hosts, sandfly vectors and leishmanial strains in the Negev, Central Arava and along the Dead Sea. Trans. R. Soc. trop. Med. Hyg. 78, 480–484.
Schnur L. F. (1977) Insect flagellate excreted factors from leptomonad, crithidial and herpetomonad strains, J. Protozool. 24, 5A–6A.
Schnur L. F. (1982) The immunological identification and characterization of leishmanial stocks and strains, with special reference to excreted factor serotyping. In Biochemical Characterization of Leishmania (Edited by Chance M. L. and Walton B. C.), pp. 25–47. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva.
Schnur L. F., Chance M. L., Ebert F., Thomas S. C. and Peters W. (1981) The biochemical and serological taxonomy of visceralizing Leishmania. Ann. trop. Med. Parasit. 75, 131–144.
Schnur L. F. and Le Blancq S. M. (1986) The serological and enzymological characterisation of aetiological agents of leishmaniasis in Israel. Annls Parasit, hum. comp. In press.
Schnur L. F., Morsy T. A., Feinsod F. M. and El Missiry A. G. (1985) Is Leishmania major the cause of infantile kala-azar in Alexandria, Egypt?
Schnur L. F. and Zuckerman A. (1977) Leishmanial excreted factor (EF) serotypes in Sudan, Kenya and Ethiopia. Ann. trop. Med. Parasit. 71, 273–294.
Schnur L. F., Zuckerman A. and Greenblatt C. L. (1972) Leishmanial serotypes as distinguished by the gel diffusion of factors excreted in vitro and in vivo. Israel J. med. Sci. 8, 932–942.
Schnur L. F., Zuckerman A. and Montilio B. (1973) Dissemination of leishmanias to the organs of Syrian hamsters following intrasplenic inoculation of promastigotes. Expl Parasit. 34, 432–447.
Schottelius J. (1982) Lectin binding strain-specific carbohydrates on the cell surfaces of Leishmania strains from the Old World. Z. Parasitenkd. 66, 237–247.
Shaw J. J. (1982) Taxonomy of the genus Leishmania: Traditionalist’s View and Modern Concepts. In Biochemical Characterization of Leishmania (Edited by Chance M. L. and Walton B. C.), pp. 9–24. UNDP/World Bank/WHO Special Programme in Research and Training in Tropical Diseases, Geneva.
Shaw J. J. and Lainson R. (1976) Leishmaniasis in Brazil: XI. Observations on the morphology of Leishmania of the braziliensis and mexicana complexes. J. trop. Med. Hyg. 76, 9–13.
Sneath P. H. A. (1964) New approaches to bacterial taxonomy: Use of computers. A. Rev. Microbiol. 18, 335–346.
Sneath P. H. A. and Sokal R. R. (1962) Numerical taxonomy. Nature 193, 855–860.
Sneath P. H. A. and Sokal R. R. (1973) Numerical Taxonomy. Freeman, San Francisco.
Spithill T. W., Grumont R. J. and Mitchell G. F. (1984) Characterization of isolates and clones of Leishmania by analysis of kinetoplast DNA. J. cell. Biochem. 24, 103–112.
Stäuber L. A. (1958) Host resistance to the Khartoum strain of Leishmania donovani. Rice Inst. Pamph. 45, 80–96.
Stäuber L. A. (1966) Characterisation of strains of Leishmania donovani. Expl Parasit. 18, 1–11.
Tait A. (1980) Evidence for diploidy and mating in trypanosomes. Nature 287, 536–538.
Turk J. L. and Belehu A. (1974) Immunological spectra in infectious diseases. In Parasites in the Immunized Host Mechanisms of Survival, Ciba Foundation Symposium 25 (new series), pp. 101–122. Associated Scientific Publishers, Amsterdam.
Turk J. L. and Bryceson A. D. M. (1971) Immunological phenomena in leprosy and related diseases. Adv. Immun. 13, 209–266.
Vessal M., Rezai H. R. and Pakzad P. (1974) Leishmania species: fatty acid composition of promastigotes. Expl Parasit. 36, 455–461.
Vickerman K. (1976) The diversity of the kinetoplastid flagellates. In Biology of the Kinetoplastida, Vol. 1 (Edited by Lumsden W. H. R. and Evans D. A.), pp. 1–34. Academic Press, New York.
Walton B. C. (1984) Application of biochemical and molecular biology techniques to problems of identification and taxonomy of Leishmania. In New Approaches to the Identification of Parasites and Their Vectors, Tropical Diseases Research Series Vol. 5 (Edited by Newton B. M. and Michal F.), pp. 277–292. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva.
Wilson V. C. L. S. and Southgate B. A. (1979) Lizard Leishmania. In Biology of the Kinetoplastida, Vol. 2 (Edited by Lumsden W. H. R. and Evans D. A.), pp. 241–268. Academic Press, London.
Wirth D. F. and McMahon-Pratt D. (1982) Rapid identification of Leishmania species by specific hybridization of kinetoplast DNA in cutaneous lesions. Proc. natn. Acad. Sci. U.S.A. 79, 6999–7003.
WHO (1984) The Leishmaniases. In Technical Report Series 701. World Health Organization, Geneva.
Yakimoff W. L. and Schokhor N. I. (1914) Recherches sur les maladies tropicales humaine et animales au Turkestan russe. C.r. Séanc. Soc. Biol. Med. 25, 196–197.
Zuckerman A. and Lainson R. (1977) Leishmania. In Parasitic Protozoa, Vol. I (Edited by Kreier J. P.), pp. 57–133. Academic Press, New York.
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Schnur, L.F. Identity and Taxonomy Within the Genus Leishmania. Int J Trop Insect Sci 7, 213–223 (1986). https://doi.org/10.1017/S1742758400008985
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DOI: https://doi.org/10.1017/S1742758400008985
Key Words
- Leishmania
- identification
- biological
- serological and biochemical characterization
- taxonomy
- phylogeny
- sexuality