Conclusions
MPI has weathered many challenges over the decades, and, with advances such as gated SPECT acquisition, technetium radiotracers, and attenuation correction software, it has overcome many of its shortcomings to remain a cornerstone of noninvasive cardiac imaging, which has high diagnostic accuracy in women.14
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References
AHA. Heart disease and stroke statistics-2004 update. Dallas: AHA; 2004.
Stramba-Badiale M, Fox KM, Priori SG, Collins P, Daly C, Graham I, et al. Cardiovascular diseases in women: a statement from the policy conference of the ESC. Eur Heart J 2006;27:994- 1005.
Mosca L, Grundy S, Judelson D, King K, Limacher M, Oparil S. AHA/ACC scientific statement: consensus panel statement. Guide to preventive cardiology for women. Circulation 1999;99:2480–4.
Daly C, Clemens F, Lopez Sendon JL, Tavazzi L, Boersma E, Danchin N, et al. Gender differences in the management and clinical outcome of stable angina. Circulation 2006;113:490–8.
Noel Bairey Merz C, Shaw LJ, Reis SE, Bittner V, Kelsey SF, Olson M, et al. Insights from the NHBLI sponsored Women’s Ischaemic Syndrome Evaluation (WISE) study Part II. J Am Coll Cardiol 2006;47(Suppl):21S-9S.
Underwood SR, Anagnostopoulos C, Cerqueira MC, Ell PJ, Flint EJ, Harbinson M, et al. Myocardial perfusion scintigraphy: the evidence. Eur J Nucl Mol Imaging 2004;31:261–91.
Conroy RM, Pyorala K, Fitzgerald AP, Sans S, Menotti A, De Becker G, et al. Estimation of ten year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J 2003;24:987–1003.
Hendel RC. Attenuation correction: eternal dilemma or real improvement. Q J Nucl Med Mol Imaging 2005;49:30–42.
Taillefer R, DePuey EG, Udelson JE, Beller GA, Latour Y, Reeves F. Comparative diagnostic accuracy of Tl-201 and Tc-99m sestamibi SPECT imaging (perfusion and ECG-gated SPECT) in detecting coronary artery disease in women. J Am Coll Cardiol 1997;29:69–77.
Mieres JM, Shaw LJ, Arai A, Budoff MJ, Flamm SD, Hundley WG, et al. Role of noninvasive testing in the clinical evaluation of women with suspected coronary artery disease. AHA scientific statement. Circulation 2005;111:682–96.
Kim C, Kwok YS, Saha S, Redberg RF. Diagnosis of suspected coronary artery disease in women. A cost-effectiveness analysis. Am Heart J 1999;137:1019–27.
de Bono D. Investigation and management of stable angina: revised guidelines 1998 of Joint Working Party of the British Cardiac Society and Royal College of Physicians of London. Heart 1999;81:546–55.
Shaw LJ, Hachamovitch R, Heller GV, Marwick TH, Tranuin MI, Iskandrian AE, et al. Noninvasive strategies for the estimation of cardiac risk in stable chest pain patients. The Economics of Noninvasive Diagnosis (END) Study group. Am J Cardiol 2000; 86:1–7.
Shaw LJ, Iskandrian AE. Prognostic value of stress SPECT. J Nucl Cardiol 2004;11:171–85.
Giri S, Shaw LJ, Berman DS. Impact of diabetes on the risk stratification using stress single-photon emission computed tomography myocardial perfusion imaging in patients with symptoms suggestive of coronary artery disease. Circulation 2002;105:32–40.
Wackers FJ, Young LH, Inzucchi SE, Chyun DA, Davey JA, Barrett EJ, et al. Detection of silent myocardial ischemia in asymptomatic diabetic subjects: the DIAD study. Diabetes Care 2004;27:1954–61.
Taylor AJ, Merz CN, Udelson JE. 34th Bethesda Conference: executive summary-can atherosclerosis imaging techniques improve the detection of patients at risk for ischemic heart disease. J Am Coll Cardiol 2003;41:1860–2.
Anand DV, Lim E, Raval U, Lipkin D, Lahiri A. Prevalence of silent myocardial ischemia in asymptomatic individuals with subclinical atherosclerosis detected by electron beam tomography. J Nucl Cardiol 2004;11:450–7.
Shaw LJ, Vasey C, Sawada S, Rimmerman C, Marwick TH. Impact of gender on risk stratification by exercise and dobutamine stress echocardiography: long-term mortality in 4234 women and 6898 men. Eur Heart J 2005;26:447–56.
National Institute of Clinical Excellence. Angina and myocardial infarction-myocardial perfusion scintigraphy. Available from: URL: http://www.nice.org.uk/TA073. Accessed February 8, 2006.
Jeetley, P, Hickman M, Kamp O, Lang RM, Thomas JD, Vannan MA, et al. Myocardial contrast echocardiography for the detection of coronary artery stenosis: a prospective multicenter study in comparison with single-photon emission computed tomography. J Am Coll Cardiol 2006;47:141–5.
Berman DS, Hachamovitch R, Shaw LJ, Friedman JD, Hayes SW, Thomson LE, et al. Roles of nuclear cardiology, cardiac computed tomography, and cardiac magnetic resonance: assessment of patients with suspected coronary artery disease. J Nucl Med 2006; 47:74–82.
Panting JR, Gatehouse PD, Yang GZ, Grothues F, Firmin DN, Collins P, et al. Abnormal subendocardial perfusion in cardiac syndrome X detected by cardiovascular magnetic resonance imaging. N Eng J Med 2002;346:1948–53.
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Naidoo, V.V. Review of gated SPECT imaging in women with suspected coronary heart disease. J Nucl Cardiol 13, 474–479 (2006). https://doi.org/10.1016/j.nuclcard.2006.06.133
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DOI: https://doi.org/10.1016/j.nuclcard.2006.06.133