Abstract
Study Design
Case report.
Introduction
De novo giant pleomorphic adenoma is a rare tumor of the parapharyngeal space (PPS). Tumors of the PPS can grow to a large size, compromising the space of the upper aerodigestive tract. However, involvement of the paravertebral region is unexpected. In extremely exceptional circumstances, these tumors can produce spinal deformity.
Case Report
A 25-year-old man presented with a longstanding mass in the neck and oral cavity. He had complaints of dysphagia, snoring, and restricted neck movements because of the large size of the tumor. Imaging showed a large mass occupying the PPS extending to the paravertebral region and causing deformity of the cervical spine. Excision was done uneventfully via a minimal access transcervical approach. Residual spinal deformity dealt with postoperative physiotherapy with improvement in lordosis and lateral tilt. No tumor recurrence occurred till 26 months of follow-up.
Conclusion
Tumors of the PPS can grow to a large size and involve the neck and PPS, even causing spinal deformity. Careful evaluation is required for ascertaining the origin of the tumor and deciding the treatment plan.
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References
Hugues III KV, Olsen KD, McCafferey TV. Parapharyngeal space neoplasms. Head Neck 1995;17:2.
Hakeem AH, Hazarika B, Pradhan SA, et al. Primary pleomorphic adenoma of minor salivary gland in the parapharyngeal space. World J Surg Oncol 2009;7:85.
Stambuk HE, Patel SG. Imaging of the parapharyngeal space. Otolaryngol Clin North Am 2008;41:77–101.
Mendelsohn AH, Bhuta S, Calcaterra TC, et al. Parapharyngeal space pleomorphic adenoma: a 30-year review. Laryngoscope 2009;119: 2170–4.
Khafif A, Segev Y, Kaplan DM. Surgical management of parapharyngeal space tumours: a 10-year review. Otolaryngol Head Neck Surg 2005;132:401–6.
Datarkar AN, Deshpande A. Giant parapharyngeal space pleomorphic adenoma of the deep lobe of parotid presenting as obstructive sleep apnoea: a case report & review of the diagnostic and therapeutic approaches. J Maxillofac Oral Surg 2015;14:532–7.
Bisht SS, Luthra M, Agarwal V, et al. Giant parapharyngeal space pleomorphic adenoma causing acute airway obstruction. Oman Med J 2017;32:240–2.
Malhotra V, Arora N, Rai V. Largest de novo parapharyngeal pleomorphic adenoma: a rare case removed via minimal access approach. Ann Maxillofac Surg 2017;7:132–5.
Gupta A, Chazen JL, Phillips CD. Imaging evaluation of the parapharyngeal space. Otolaryngol Clin North Am 2012;45:1223–32.
Mondal A, Roychoudhari BK. Per oral fine needle aspiration cytology of parapharyngeal lesions. Acta Cytol 1993;37:694–8.
Malone JP, Agarwal A, Schuller DE. Safety and efficacy of transcervical resection of parapharyngeal space neoplasms. Ann Otol Rhinol Laryngol 2001;110:1093–8.
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Author disclosures: PS (none), PR (none), IS (none), SM (none).
IRB approval: No copyrighted material was included in this study. Patient’s identity has not been revealed. Being a single case study, it is exempt from institutional review board approval.
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Sagar, P., Rajpurohit, P., Singh, I. et al. Giant De Novo Pleomorphic Adenoma of Parapharyngeal Space, Can It Cause Spinal Deformity? A Case Report. Spine Deform 7, 505–508 (2019). https://doi.org/10.1016/j.jspd.2018.09.009
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DOI: https://doi.org/10.1016/j.jspd.2018.09.009