Abstract
Study Design
Single-center retrospective review of spinal deformity patients undergoing removal of infected posterior spinal fusion implants over a 10-year period.
Objective
To evaluate the intraoperative blood loss and perioperative complications of implant removal in posterior spinal fusions.
Summary of Background Data
To our knowledge, no studies examine blood loss or complications associated with removal of infected spinal implants in spinal deformity.
Methods
A retrospective review of 28 consecutive cases of infected posterior spinal fusion implant removal from 2003 to 2012 was performed. Exclusion criteria were patients with ≤6 levels of instrumentation, a partial removal of implants or a bleeding disorder.
Results
The average estimated blood loss was 465 mL (range 100–1,505 mL). Average estimated blood volume was 3,814 mL (range 1,840–9,264 mL). The average percentage of estimated blood loss was 14.2% (range 1.9%–43.5%). On postoperative labs obtained at the conclusion of the procedure, there was an average loss in hematocrit of 6.6 from preoperative values. Seventy-one percent of patients (20/28) received a blood transfusion; 39% (11/28) of these received a transfusion intraoperatively and 54% (15/28) received a transfusion postoperatively. Forty-six percent of patients (13/28) experienced an associated medical complication in the postoperative period. Among these 13, there were 16 total complications, with the most common being seizures (4/16), pneumonia (2/16), and sepsis (2/16). Average hospital stay was 14 days (range 4–52).
Conclusion
Seventy-one percent of patients undergoing removal of infected spinal implants received a blood transfusion. We recommend having blood products available when removing posterior spinal instrumentation >6 levels. Patients and families should be counseled on the high risk of complications and expected hospital stay in these cases.
Level of Evidence
Level III.
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References
Mackenzie WG, Matsumoto H, Williams BA, et al. Surgical site infection following spinal instrumentation for scoliosis: a multicenter analysis of rates, risk factors, and pathogens. J Bone Joint Surg Am 2013;95:800–6. S801-2.
Reames DL, Smith JS, Fu KM, et al. Complications in the surgical treatment of 19,360 cases of pediatric scoliosis: a review of the Scoliosis Research Society Morbidity and Mortality database. Spine 2011;36:1484–91.
Hicks JM, Singla A, Shen FH, Arlet V. Complications of pedicle screw fixation in scoliosis surgery: a systematic review. Spine 2010;35:E465–70.
Ialenti MN, Lonner BS, Verma K, et al. Predicting operative blood loss during spinal fusion for adolescent idiopathic scoliosis. J Pediatr Orthop 2013;33:372–6.
Kim YJ, Lenke LG, Cho SK, et al. Comparative analysis of pedicle screw versus hook instrumentation in posterior spinal fusion of adolescent idiopathic scoliosis. Spine 2004;29:2040–8.
Ledonio CG, Polly Jr DW, Vitale MG, et al. Pediatric pedicle screws: comparative effectiveness and safety: a systematic literature review from the Scoliosis Research Society and the Pediatric Orthopaedic Society of North America task force. J Bone Joint Surg 2011;93:1227–34.
Mueller TL, Miller NH, Baulesh DM, et al. The safety of spinal pedicle screws in children ages 1 to 12. Spine J 2013;13:894–901.
Upasani VV, Caltoum C, Petcharaporn M, et al. Adolescent idiopathic scoliosis patients report increased pain at five years compared with two years after surgical treatment. Spine 2008;33:1107–12.
Erickson MA, Morrato EH, Campagna EJ, et al. Variability in spinal surgery outcomes among children’s hospitals in the United States. J Pediatr Orthop 2013;33:80–90.
Fu KM, Smith JS, Polly DW, et al. Morbidity and mortality associated with spinal surgery in children: a review of the Scoliosis Research Society morbidity and mortality database. J Neurosurg Pediatr 2011;7:37–41.
Busam ML, Esther RJ, Obremskey WT. Hardware removal: indications and expectations. J Am Acad Orthop Surg 2006;14:113–20.
Sanderson PL, Ryan W, Turner PG. Complications of metalwork removal. Injury 1992;23:29–30.
Gatch WD, Little WD. Amount of blood loss during some of the more common operations. JAMA 1924;83:1075–6.
Blain AW. Impressions resulting from three thousand transfusions of unmodified blood. Ann Surg 1929;89:189.
Brecher ME, Monk T, Goodnough LT. A standardized method for calculating blood loss. Transfusion 1997;37:1070–4.
Mooney JF, Barfield WR. Validity of estimates of intraoperative blood loss in pediatric spinal deformity. Spine Deform 2013;1:21–4.
Chen Y, Tai BC, Nayak D, et al. Blood loss in spinal tumour surgery and surgery for metastatic spinal disease: a meta-analysis. Bone Joint J 2013;95–B:683–8.
Murray DJ, Forbes RB, Titone MB, Weinstein SL. Transfusion management in pediatric and adolescent scoliosis surgery. Efficacy of autologous blood. Spine 1997;22:2735–40.
Woods BI, Rosario BL, Chen A, et al. The association between perioperative allogeneic transfusion volume and postoperative infection in patients following lumbar spine surgery. J Bone Joint Surg 2013;95:2105–10.
Long TR, Stans AA, Shaughnessy WJ, et al. Changes in red blood cell transfusion practice during the past quarter century: a retrospective analysis of pediatric patients undergoing elective scoliosis surgery using the Mayo database. Spine J 2012;12:455–62.
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LMA (other from Eli Lily, nonfinancial support from POSNA Committee Member, outside the submitted work); ERAJ (none); KS (grants from POSNA & SRS, personal fees from Biomet, Medtronic, nonfinancial support from Growing Spine Study Group, Scoliosis Research Society, Growing Spine Foundation Medtronic Strategic Advisory Board; Scoliosis Research Society, personal fees from expert testimony, personal fees from Biomet, Medtronic, Stryker, Wolters Kluwer Health–Lippincott Williams & Wilkins, other from Medtronic, other from Stryker; Biomet, Medtronic, outside the submitted work; in addition, KS has a patent Medtronic issued, and Father is coauthor DLS); LRH (none); AMB (none); AW (none); DLS (grants from POSNA & SRS, personal fees from Biomet, Medtronic, nonfinancial support from Growing Spine Study Group, Scoliosis Research Society, Growing Spine Foundation Medtronic Strategic Advisory Board, personal fees from expert testimony, personal fees from Biomet, Medtronic, Stryker, personal fees from Wolters Kluwer Health–Lippincott Williams & Wilkins, other from Medtronic, other from Stryker; Biomet, Medtronic, outside the submitted work; in addition, DLS has a patent Medtronic issued).
IRB Approval from Children’s Hospital Los Angeles has been obtained for this study.
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Andras, L.M., Joiner, E.R.A., Skaggs, K. et al. Removal of Infected Posterior Spinal Implants: Be Prepared to Transfuse. Spine Deform 4, 283–287 (2016). https://doi.org/10.1016/j.jspd.2016.01.002
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DOI: https://doi.org/10.1016/j.jspd.2016.01.002